Evidence map›Paper›PMID 21359399›Full record

ArticleOrganic & biomolecular chemistry2011

Sequential two-step multienzyme synthesis of tumor-associated sialyl T-antigens and derivatives.

Kam Lau, Hai Yu, Vireak Thon, Zahra Khedri, Meghan E Leon, Bao K Tran, Xi Chen

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Tandem sialoglycan-binding modules in aThe Journal of biological chemistry · 2020
    Article
  4. Article
  5. Review
  6. Synthesis ofFrontiers in immunology · 2019
    Review
  7. Article
  8. Article
  9. Article
  10. Human Milk Oligosaccharides (HMOS): Structure, Function, and Enzyme-Catalyzed Synthesis.Advances in carbohydrate chemistry and biochemistry · 2015
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kam LauDepartment of Chemistry, University of California, One Shields Avenue, Davis, California, USA.
Hai Yu
Vireak Thon
Zahra Khedri
Meghan E Leon
Bao K Tran
Xi Chen
University of California, Davis · US

Funding

Neu5Gc and anti-Neu5Gc antibodies for detection of cancer and cancer riskU01CA128442 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 2007 to 2011
$2.1M
Studies of Naturally Occurring Structurally Modified CarbohydratesR01GM076360 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI · 2006 to 2010
$1.9M
NCI NIH HHS U01 CA128442NCI NIH HHS U01CA128442NIGMS NIH HHS R01 GM076360NIGMS NIH HHS R01GM076360
6 · The paper itself

Abstract

A series of α2-3-sialylated β1-3-linked galactosides, including sialyl T-antigens, 3'-sialyl galacto-N-biose, 3'-sialyl lacto-N-biose, and their derivatives containing natural and non-natural sialic acid forms have been synthesized from simple monosaccharides using an efficient sequential two-step multienzyme approach.

Indexed as

Antigens, NeoplasmBifidobacteriumGalactosidesGalactosyltransferasesMolecular StructureN-Acetylneuraminic AcidPasteurellaSialyltransferasesAntigens, Neoplasmbeta-1,3-galactosyl-N-acetylhexosamine phosphorylaseGalactosidesGalactosyltransferasesN-Acetylneuraminic AcidSialyltransferases

Identifiers

PMID21359399
PMCPMC3114947
OpenAlexW2013912440

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.