ArticlePloS one2011
Molecular epidemiology of a Pseudomonas aeruginosa hospital outbreak driven by a contaminated disinfectant-soap dispenser.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 101 citations in OpenAlex.
- Eleven-Year Trends in Antimicrobial Resistance and Isolation Rates per 1000 Patient-Days of Key Gram-Positive and Gram-Negative Bacteria in a Tertiary Care Hospital in Türkiye (2014-2024).Infectious diseases & clinical microbiology · 2026Article
- A plasmid-encoded detoxification system contributing to the survival ofApplied and environmental microbiology · 2026Article
- Significance of Whole-Genome Sequencing for the Traceability of Foodborne Pathogens: During the Processing of Meat and Dairy Products.Foods (Basel, Switzerland) · 2025Review
- The diadenosine tetraphosphate hydrolase ApaH contributes to Pseudomonas aeruginosa pathogenicity.PLoS pathogens · 2024Article
- S2k-Guideline hand antisepsis and hand hygiene.GMS hygiene and infection control · 2024Article
- Resistance inAntibiotics (Basel, Switzerland) · 2023Review
- A loophole in soap dispensers mediates contamination with Gram-negative bacteria.MicrobiologyOpen · 2023Article
- Growth of Gram-Negative Bacteria in Antiseptics, Disinfectants and Hand Hygiene Products in Two Tertiary Care Hospitals in West Africa-A Cross-Sectional Survey.Pathogens (Basel, Switzerland) · 2023Article
- Colorimetric bacteria sensing of Pseudomonas aeruginosa using gold nanoparticle probes.Journal, genetic engineering & biotechnology · 2023Article
- Pseudomonas aeruginosa isolation from dog grooming products used by private owners or by professional pet grooming salons: prevalence and risk factors.Veterinary dermatology · 2022Article
- Development of Quality Control Ranges for Biocide Susceptibility Testing.Pathogens (Basel, Switzerland) · 2022Article
- Molecular typing of clinical and environmental isolates ofIranian journal of basic medical sciences · 2022Article
- β-lactam Resistance inPathogens (Basel, Switzerland) · 2021Review
- Chlorhexidine leads to the evolution of antibiotic-resistant Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Triclosan Tolerance Is Driven by a Conserved Mechanism in DiverseApplied and environmental microbiology · 2021Article
- Persistence of Pathogens on Inanimate Surfaces: A Narrative Review.Microorganisms · 2021Review
- Why? - Successful Pseudomonas aeruginosa clones with a focus on clone C.FEMS microbiology reviews · 2020Review
- Adoption of recommended hand hygiene practices to limit zoonotic disease transmission at agricultural fairs.Preventive veterinary medicine · 2020Article
- Prevalence of antibiotic-resistant, toxic metal-tolerant and biofilm-forming bacteria in hospital surroundings.Environmental analysis, health and toxicology · 2020Article
- Multi-drug resistant Pseudomonas aeruginosa and Klebsiella pneumoniae circulation in a burn hospital, Tehran, Iran.GMS hygiene and infection control · 2019Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivePseudomonas aeruginosa infection represents a main cause of morbidity and mortality among immunocompromised patients. This study describes a fatal epidemic of P. aeruginosa that occurred in a hematology unit in Italy.
methodsRetrospective cohort study, prospective surveillance, auditing, extensive testing on healthcare workers and environmental investigation were performed to define the dynamics and potential causes of transmission. RAPD, macrorestriction analyses and sequence typing were used to define relationships between P. aeruginosa isolates.
resultsEighteen cases of infection were identified in the different phases of the investigation. Of these, five constitute a significant molecular cluster of infection. A P. aeruginosa strain with the same genetic fingerprint and sequence type (ST175) as clinical isolates strain was also isolated from a heavily contaminated triclosan soap dispenser. DISCUSSION AND
conclusionsOur results are consistent with the hypothesis that patients became indirectly infected, e.g., during central venous catheter handling through contaminated items, and that the triclosan soap dispenser acted as a common continuous source of P. aeruginosa infection. Since P. aeruginosa is intrinsically unsusceptible to triclosan, the use of triclosan-based disinfectant formulations should be avoided in those healthcare settings hosting patients at high risk of P. aeruginosa infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.