Evidence map›Paper›PMID 21359193›Full record

Trial reportPloS one2011

Iodine deficiency in northern Paris area: impact on fetal thyroid mensuration.

Dominique Luton, Corinne Alberti, Edith Vuillard, Guillaume Ducarme, Jean François Oury, Jean Guibourdenche

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00162539 (Relation Between Maternal Iodine Status and Prenatal Foetal Thyroid Dimension), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00162539 nacompletednot on this map

Relation Between Maternal Iodine Status and Prenatal Foetal Thyroid Dimension

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2005 to 2006Enrolled130ConditionsDeficiency DiseaseArmsechography
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
  9. The changing epidemiology of iodine deficiency.Nature reviews. Endocrinology · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Dominique LutonUniversité Paris VII, AP-HP, GHU Nord, Hôpital Beaujon, Service de Gynécologie Obstétrique, Clichy, France. dluton@free.fr
Corinne Alberti
Edith Vuillard
Guillaume Ducarme
Jean François Oury
Jean Guibourdenche
Assistance Publique – Hôpitaux de Paris · FRUniversité Paris Cité · FRHôpital Beaujon · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIodine is essential for normal fetal and neonatal development. We studied the prevalence and impact on fetal thyroid development of iodine deficiency in pregnant women in the northern part of the Paris conurbation. MATERIALS AND

methods110 patients underwent several determinations of urinary iodine excretion (UIE) and of serum FT4, FT3, and TSH. Fetal thyroid gland size was assessed using ultrasonography.

resultsWe found evidence of widespread iodine deficiency (mean UIE, 49.8 µg/L [standard deviation, 2.11]). Iodine deficiency did not correlate significantly with maternal thyroid parameters but showed a significant negative correlation with fetal thyroid gland size (rho = 0.25, P = 0.02).

conclusionIodine deficiency during pregnancy is still a problem in our geographical area and affects the fetal thyroid gland. Clinical Trials.gov NCT00162539.

Indexed as

AlgorithmsFemaleFetusGestational AgeHumansIodineOrgan SizeParisPregnancyPregnancy ComplicationsThyroid DiseasesThyroid Function TestsThyroid GlandUltrasonography, PrenatalIodine

Identifiers

PMID21359193
PMCPMC3040245
OpenAlexW2059056909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.