Evidence map›Paper›PMID 21357809›Full record

Trial reportArchives of internal medicine2011

Delivery and outcomes of a yearlong home exercise program after hip fracture: a randomized controlled trial.

Denise L Orwig, Marc Hochberg, Janet Yu-Yahiro, Barbara Resnick, William G Hawkes, Michelle Shardell, J Richard Hebel, Perry Colvin, Ram R Miller, Justine Golden and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Archives of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00390741 (Bone/Muscle Changes Following Hip Fracture in Older White Women), which is not on this map. Cited by 44 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00390741 nacompletednot on this map

Bone/Muscle Changes Following Hip Fracture in Older White Women

TypeinterventionalSponsorUniversity of Maryland, BaltimoreRan1998 to 2005Enrolled170ConditionsHip FractureArmsExercise Plus Program
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Effectiveness of exercise rehabilitation interventions on depressive symptoms in older adults post hip fracture: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Interventions for improving mobility after hip fracture surgery in adults.The Cochrane database of systematic reviews · 2022
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Interventions for preventing falls in older people living in the community.The Cochrane database of systematic reviews · 2012
    Pooled it
  10. Health-related quality of life after hip fracture: effects of a 12-month home-based exercise intervention-secondary analyses of an RCT.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Trial
  11. Trial
  12. Trial
  13. Effects of a simple home exercise program and vitamin D supplementation on health-related quality of life after a hip fracture: a randomized controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Meaningful improvement in gait speed in hip fracture recovery.Journal of the American Geriatrics Society · 2011
    Trial
  19. Serum vitamin E concentrations and recovery of physical function during the year after hip fracture.The journals of gerontology. Series A, Biological sciences and medical sciences · 2011
    Trial
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Denise L OrwigDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, 21201, USA. dorwig@epi.umaryland.edu
Marc Hochberg
Janet Yu-Yahiro
Barbara Resnick
William G Hawkes
Michelle Shardell
J Richard Hebel
Perry Colvin
Ram R Miller
Justine Golden
Sheryl Zimmerman
Jay Magaziner

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Sequelae of Hip Fracture in Men: An Epidemiologic StudyR37AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY · 1992 to 2018
$11.3M
RESEARCH TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000262 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ANN L GRUBER-BALDINI, DENISE L ORWIG · 1998 to 2026
$8.2M
UPPER EXTREMITY TRAINING FOR CHRONIC STROKEP60AG012583 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLDBERG, ANDREW P · 1994 to 2005
$7.8M
Determinants of Recovery Following Hip FractureR01AG018668 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY STEVEN · 2001 to 2004
$2.3M
TESTING THE EXERCISE PLUS PROGRAM FOLLOWING HIP FRACTURER01AG017082 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RESNICK, BARBARA M · 1999 to 2002
$1.6M
DETERMINANTS OF RECOVERY FROM HIP FX/SUP BONE/MUSCLER55AG009901 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI MAGAZINER, JAY STEVEN · 1991 to 1991
–
NIA NIH HHS P30 AG028747NIA NIH HHS P60 AG012583NIA NIH HHS P60 AG12583NIA NIH HHS R01 AG017082NIA NIH HHS R01 AG018668NIA NIH HHS R01 AG17082NIA NIH HHS R01 AG18668NIA NIH HHS R37 AG009901NIA NIH HHS R37 AG09901NIA NIH HHS T32 AG000262NIA NIH HHS T32 AG00262
6 · The paper itself

Abstract

backgroundHip fracture affects more than 1.6 million persons worldwide and causes substantial changes in body composition, function, and strength. Usual care (UC) has not successfully restored function to most patients, and prior research has not identified an effective restorative program. Our objective was to determine whether a yearlong home-based exercise program initiated following UC could be administered to older patients with hip fracture and improve outcomes.

methodsA randomized controlled trial of 180 community dwelling female patients with hip fracture, 65 years and older, randomly assigned to intervention (n = 91) or UC (n = 89). Patients were recruited within 15 days of fracture from 3 Baltimore-area hospitals from November 1998 through September 2004. Follow-up assessments were conducted at 2, 6, and 12 months after fracture. The Exercise Plus Program was administered by exercise trainers that included supervised and independently performed aerobic and resistive exercises with increasing intensity. Main outcome measures included bone mineral density of the contralateral femoral neck. Other outcomes included time spent and kilocalories expended in physical activity using the Yale Physical Activity Scale, muscle mass and strength, fat mass, activities of daily living, and physical and psychosocial functioning. The effect of intervention for each outcome was estimated by the difference in outcome trajectories 2 to 12 months after fracture.

resultsMore than 80% of participants received trainer visits, with the majority receiving more than 3 quarters (79%) of protocol visits. The intervention group reported more time spent in exercise activity during follow-up (P < .05). Overall, small effect sizes of 0 to 0.2 standard deviations were seen for bone mineral density measures, and no significant patterns of time-specific between-group differences were observed for the remaining outcome measures.

conclusionPatients with hip fracture who participate in a yearlong, in-home exercise program will increase activity level compared with those in UC; however, no significant changes in other targeted outcomes were detected.

trial registrationclinicaltrials.gov Identifier: NCT00390741.

Indexed as

Exercise TherapyAgedAged, 80 and overDelivery of Health CareFeasibility StudiesFemaleHip FracturesHumansProgram EvaluationTreatment Outcome

Identifiers

PMID21357809
PMCPMC3140167

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.