Trial reportArchives of internal medicine2011
Preventing weight gain by lifestyle intervention in a general practice setting: three-year results of a randomized controlled trial.
Trial report in Archives of internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- European guideline on obesity care in patients with gastrointestinal and liver diseases - Joint European Society for Clinical Nutrition and Metabolism / United European Gastroenterology guideline.United European gastroenterology journal · 2022Guideline
- Therapeutic Treatment for Abdominal Obesity in Adults.Deutsches Arzteblatt international · 2018Pooled it
- Randomized Trials of Nurse-Delivered Interventions in Weight Management Research: A Systematic Review.Western journal of nursing research · 2017Pooled it
- Pooled it
- Technology-assisted weight loss interventions in primary care: a systematic review.Journal of general internal medicine · 2015Pooled it
- Transtheoretical model stages of change for dietary and physical exercise modification in weight loss management for overweight and obese adults.The Cochrane database of systematic reviews · 2014Pooled it
- Effects of nutrition education on weight gain prevention: a randomized controlled trial.Nutrition journal · 2016Trial
- Pre-treatment circulating leptin/ghrelin ratio as a non-invasive marker to identify patients likely to regain the lost weight after an energy restriction treatment.Journal of endocrinological investigation · 2014Trial
- Randomized controlled trial on cardiovascular risk management by practice nurses supported by self-monitoring in primary care.BMC family practice · 2012Trial
- Community-Based BMI Screening for Overweight and Obesity in Adults Aged 35 Years and Older in Malaysia: Regression Discontinuity Analysis.JMIR public health and surveillance · 2025Article
- Tools to guide clinical discussions on physical activity, sedentary behaviour, and/or sleep for health promotion between primary care providers and adults accessing care: a scoping review.BMC primary care · 2023Article
- Pharmacotherapy for Obesity-Trends Using a Population Level National Database.Obesity surgery · 2021Article
- SMART: Study protocol for a sequential multiple assignment randomized controlled trial to optimize weight loss management.Contemporary clinical trials · 2019Article
- Health advice and education given to overweight patients by primary care doctors and nurses: A scoping literature review.Preventive medicine reports · 2019Article
- Role of the family doctor in the management of adults with obesity: a scoping review.BMJ open · 2018Article
- Comparison among criteria to define successful weight-loss maintainers and regainers in the Action for Health in Diabetes (Look AHEAD) and Diabetes Prevention Program trials.The American journal of clinical nutrition · 2017Article
- Determinants of weight gain prevention in young adult and midlife women: study design and protocol of a randomized controlled trial.JMIR research protocols · 2015Article
- Interventions for body weight reduction in obese patients during short consultations: an open-label randomized controlled trial in the Japanese primary care setting.Asia Pacific family medicine · 2015Article
- High risk of obesity and weight gain for HIV-infected uninsured minorities.Journal of acquired immune deficiency syndromes (1999) · 2014Article
- Health communication cards as a tool for behaviour change.ISRN obesity · 2014Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWeight regain after initial loss of weight is common, which indicates a need for lifestyle counseling aimed at preventing weight gain instead of weight loss. This study was conducted to determine whether structured lifestyle counseling by nurse practitioners (NPs) group compared with usual care by general practitioners (GP-UC) in overweight and obese patients can prevent (further) weight gain.
methodsA randomized controlled trial in 11 general practice locations in the Netherlands of 457 patients (body mass index, 25-40 [calculated as weight in kilograms divided by height in meters squared]; mean age, 56 years; 52% female) with either hypertension or dyslipidemia or both. The NP group received lifestyle counseling with guidance of the NP using a standardized software program. The GP-UC group received usual care from their GP. Main outcome measures were changes in body weight, waist circumference, blood pressure, and fasting glucose and blood lipid levels after 3 years.
resultsIn both groups, approximately 60% of the participants achieved weight maintenance after 3 years. There was no significant difference in mean (SD) weight change and change of waist circumference between the NP and GP-UC groups (weight change: NP group, -1.2% [5.8%], and GP-UC group, -0.6% [5.6%] [P = .37]; and change of waist circumference: NP group, -0.8 [7.1] cm, and GP-UC group, 0.4 [7.2] cm [P = .11]). A significant difference occurred for mean (SD) fasting glucose levels (NP group, -0.02 [0.49] mmol/L, and GP-UC group, 0.10 [0.53] mmol/L [P = .02]) (to convert to milligrams per deciliter, divide by 0.0555) but not for lipid levels and blood pressure.
conclusionsLifestyle counseling by NPs did not lead to significantly better prevention of weight gain compared with GPs. In the majority in both groups, lifestyle counseling succeeded in preventing (further) weight gain.
trial registrationtrialregister.nl Identifier: NTR1365.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.