Evidence map›Paper›PMID 21356060›Full record

ArticleCritical care (London, England)2011

Uncalibrated pulse power analysis fails to reliably measure cardiac output in patients undergoing coronary artery bypass surgery.

Ole Broch, Jochen Renner, Jan Höcker, Matthias Gruenewald, Patrick Meybohm, Jan Schöttler, Markus Steinfath, Berthold Bein

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in Critical care (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02529033 (Comparative Hemodynamic Assessment Between Lidco Rapid and Pulmonary Artery Thermodilution), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02529033 completednot on this mapstarted 2015, after this paper: background citation

Comparative Hemodynamic Assessment Between Lidco Rapid and Pulmonary Artery Thermodilution

TypeobservationalSponsorUniversity of IowaRan2015 to 2016Enrolled64ConditionsLow Cardiac OutputArmsLIDCO Rapid, Pulmonary artery catheter
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Noninvasive pulse contour analysis for determination of cardiac output in patients with chronic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2018
    Trial
  3. Trial
  4. Observational
  5. Article
  6. Article
  7. Article
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  11. Year in review 2011: Critical Care--Cardiology.Critical care (London, England) · 2012
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ole BrochDepartment of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, Schwanenweg 21, 24105 Kiel, Germany. broch@anaesthesie.uni-kiel.de
Jochen Renner
Jan Höcker
Matthias Gruenewald
Patrick Meybohm
Jan Schöttler
Markus Steinfath
Berthold Bein
University Hospital Schleswig-Holstein · DEUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUncalibrated arterial pulse power analysis has been recently introduced for continuous monitoring of cardiac index (CI). The aim of the present study was to compare the accuracy of arterial pulse power analysis with intermittent transpulmonary thermodilution (TPTD) before and after cardiopulmonary bypass (CPB).

methodsForty-two patients scheduled for elective coronary surgery were studied after induction of anaesthesia, before and after CPB respectively. Each patient was monitored with the pulse contour cardiac output (PiCCO) system, a central venous line and the recently introduced LiDCO monitoring system. Haemodynamic variables included measurement of CI derived by transpulmonary thermodilution (CITPTD) or CI derived by pulse power analysis (CIPP), before and after calibration (CIPPnon-cal., CIPPcal.). Percentage changes of CI (ΔCITPTD, ΔCIPPnon-cal./PPcal.) were calculated to analyse directional changes.

resultsBefore CPB there was no significant correlation between CIPPnon-cal. and CITPTD (r2 = 0.04, P = 0.08) with a percentage error (PE) of 86%. Higher mean arterial pressure (MAP) values were significantly correlated with higher CIPPnon-cal. (r2 = 0.26, P < 0.0001). After CPB, CIPPcal. revealed a significant correlation compared with CITPTD (r2 = 0.77, P < 0.0001) with PE of 28%. Changes in CIPPcal. (ΔCIPPcal.) showed a correlation with changes in CITPTD (ΔCITPTD) only after CPB (r2 = 0.52, P = 0.005).

conclusionsUncalibrated pulse power analysis was significantly influenced by MAP and was not able to reliably measure CI compared with TPTD. Calibration improved accuracy, but pulse power analysis was still not consistently interchangeable with TPTD. Only calibrated pulse power analysis was able to reliably track haemodynamic changes and trends.

Indexed as

AdultAgedCalibrationCardiac OutputCoronary Artery BypassFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPostoperative CarePreoperative CarePulseReproducibility of ResultsThermodilution

Identifiers

PMID21356060
PMCPMC3222009
OpenAlexW2149812157

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.