Evidence map›Paper›PMID 21354703›Full record

ArticlePain2011

Nonmedical use of prescription opioids and pain in veterans with and without HIV.

Declan T Barry, Joseph L Goulet, Robert K Kerns, William C Becker, Adam J Gordon, Amy C Justice, David A Fiellin

Open access · greenAbstract read
In one paragraph

Article in Pain, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Declan T BarryYale University School of Medicine, New Haven, CT, USA The APT Foundation Pain Treatment Services, New Haven, CT, USA VA Connecticut Healthcare System, New Haven, CT, USA Yale University School of Public Health, Center for Interdisciplinary Research on AIDS, New Haven, CT, USA Center for Health Equity Research and Promotion (CHERP) and Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, PA, USA.
Joseph L Goulet
Robert K Kerns
William C Becker
Adam J Gordon
Amy C Justice
David A Fiellin
Yale University · USUniversity of Pittsburgh · USVA Connecticut Healthcare System · US

Funding

Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol Associated Outcomes Among HIV+/-Aging VeteransU01AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2002 to 2005
$10.1M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Models of SBIRT for Opioid Dependent Patients in the Emergency DepartmentR01DA025991 · NIDA · YALE UNIVERSITY · PI D'ONOFRIO, GAIL, FIELLIN, DAVID · 2008 to 2012
$4.8M
Buprenorphine Maintenance vs. Detoxification in Prescription Opioid DependenceR01DA020576 · NIDA · YALE UNIVERSITY · PI FIELLIN, DAVID · 2007 to 2011
$2.9M
Counseling for Primary Care Office-Based BuprenorphineR01DA019511 · NIDA · YALE UNIVERSITY · PI FIELLIN, DAVID · 2005 to 2009
$2.8M
Chronic Pain and Opioid Dependence Assessment and TreatmentK23DA024050 · NIDA · YALE UNIVERSITY · PI BARRY, DECLAN T. · 2008 to 2012
$901k
NIAAA NIH HHS U01 AA013566NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01 AA 13566NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U10 AA 13566NIDA NIH HHS K23 DA024050NIDA NIH HHS K23 DA024050-02NIDA NIH HHS R01 DA019511NIDA NIH HHS R01 DA019511-03NIDA NIH HHS R01 DA020576NIDA NIH HHS R01 DA020576-01A1NIDA NIH HHS R01 DA025991NIMH NIH HHS P30 MH062294NIMH NIH HHS P30MH062294
6 · The paper itself

Abstract

Few studies have systematically evaluated nonmedical use of prescription opioids (NMU) among U.S. military veterans, those who report pain, and those with human immunodeficiency virus (HIV). An increased understanding of the factors associated with NMU may help providers to balance maintaining patient access to prescription opioids for legitimate medical reasons and reducing the risks of addiction. We analyzed self-report data and electronic medical and pharmacy record data from 4122 participants in the Veterans Aging Cohort Study. Bivariate associations were analyzed using chi-squared tests, t tests, and median tests, and multivariable associations were assessed using logistic regression. Median participant age was 52 years; 95% were men; 65% were black, and 53% were HIV infected. NMU was reported by 13% of participants. In multivariable analysis, NMU was associated with: being Hispanic (adjusted odds ratio [AOR] 1.8); aged 40-44 years (AOR 1.6); Alcohol Use Disorders Identification Test score ≥20 (AOR 2.0); drug use disorder (AOR 1.9); opioid use disorder (AOR 2.7); past month cigarette use (AOR 1.3); receiving a past-year Veterans Health Administration opioid prescription (AOR 1.9); hepatitis C (AOR 1.5); and pain interference (AOR 1.1). Being overweight (AOR 0.6) or obese (AOR 0.5) and having a higher 12-Item Short-Form Health Survey (SF-12) Mental Component Summary (AOR 0.98) were associated with less NMU. Patients with and without NMU did not differ on HIV status or SF-12 Physical Component Summary. Veterans in care have a high prevalence of NMU that is associated with substance use, medical status, and pain interference, but not HIV status.

Indexed as

Veterans HealthAdultAgedAnalgesics, OpioidChi-Square DistributionCohort StudiesFemaleHealth SurveysHIV InfectionsHumansLogistic ModelsMaleMental DisordersMiddle AgedOdds RatioOpioid-Related DisordersAnalgesics, Opioid

Identifiers

PMID21354703
PMCPMC3086805
OpenAlexW2037870424

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.