ReviewTrends in microbiology2011
A play in four acts: Staphylococcus aureus abscess formation.
Review in Trends in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
197 citing papers in PubMed, 301 citations in OpenAlex.
- Early plaque formation on PTFE membranes with expanded or dense surface structures applied in the oral cavity of human volunteers.Clinical and experimental dental research · 2021Trial
- Gene deletions differentially affect surface-associated biofilms and staphylococcal abscess communities.Biofilm · 2026Article
- FibriLysins disrupt Staphylococcus aureus biofilms and abscess communities.Nature microbiology · 2026Article
- Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management.MedComm · 2026Review
- Monomicrobial Staphylococcus aureus Necrotizing Soft Tissue Infection: A Case Report and Review of Literature.Cureus · 2026Article
- Orthogonal cell division mediated by PcdA organizes surface virulence factors to drive staphylococcal abscess community formation.Cell reports · 2026Article
- Article
- Colocutaneous Fistula Presenting as a Lateral Thigh Mass With Secondary Prosthetic Hip Infection.Cureus · 2026Article
- Osteomyelitis.Nature reviews. Disease primers · 2026Review
- PGEThe Journal of investigative dermatology · 2026Article
- Orthogonal cell division organizes surface virulence factors to drive staphylococcal abscess community formation.bioRxiv : the preprint server for biology · 2026Article
- Fibrin barriers limit vancomycin penetration into staphylococcal abscess communities and maintainbioRxiv : the preprint server for biology · 2026Article
- The 3D landscape of infection: spatial organization andFrontiers in immunology · 2026Review
- Article
- Article
- Macrophage-derived amphiregulin induces myofibroblast transition in adipogenic lineage precursors near Staphylococcus aureus abscess in bone marrow.Nature communications · 2025Article
- Raman Monitoring ofInternational journal of molecular sciences · 2025Article
- Review
- Review
- Algal Metabolites as Novel Therapeutics Against Methicillin-ResistantPharmaceutics · 2025Review
137 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Staphylococcus aureus is an important human pathogen that causes skin and soft tissue abscesses. Abscess formation is not unique to staphylococcal infection and purulent discharge has been widely considered a physiological feature of healing and tissue repair. Here we present a different view, whereby S. aureus deploys specific virulence factors to promote abscess lesions that are distinctive for this pathogen. In support of this model, only live S. aureus is able to form abscesses, requiring genes that act at one or more of four discrete stages during the development of these infectious lesions. Protein A and coagulases are distinctive virulence attributes for S. aureus, and humoral immune responses specific for these polypeptides provide protection against abscess formation in animal models of staphylococcal disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.