ReviewTrends in molecular medicine2011
Optogenetic investigation of neural circuits in vivo.
Review in Trends in molecular medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 113 citations in OpenAlex.
- Article
- A large-scale optogenetic neurophysiology platform for improving accessibility in non-human primate behavioral experiments.Nature communications · 2026Article
- A large-scale optogenetic neurophysiology platform for improving accessibility in non-human primate behavioral experiments.bioRxiv : the preprint server for biology · 2025Article
- Opto2P-FCM: A MEMS based miniature two-photon microscope with two-photon patterned optogenetic stimulation.bioRxiv : the preprint server for biology · 2024Article
- Optogenetically engineered calcium oscillations promote autophagy-mediated cell death via AMPK activation.Open biology · 2024Article
- Optogenetic Approach in Trigeminal Neuralgia and Potential Concerns: Preclinical Insights.Molecular neurobiology · 2024Review
- Optogenetically engineered Ca2+ oscillation-mediated DRP1 activation promotes mitochondrial fission and cell death.Journal of cell science · 2023Article
- Detection of laser-associated heating in the brain during simultaneous fMRI and optogenetic stimulation.Magnetic resonance in medicine · 2023Article
- A synthetic synthesis to explore animal evolution and development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- A drivable optrode for use in chronic electrophysiology and optogenetic experiments.Journal of neuroscience methods · 2021Article
- A neuroscientist's guide to transgenic mice and other genetic tools.Neuroscience and biobehavioral reviews · 2020Review
- Molecular Mechanisms of Cancer-Induced Sleep Disruption.International journal of molecular sciences · 2019Review
- Neuronal Mechanisms for Sleep/Wake Regulation and Modulatory Drive.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Review
- Optogenetics: the new molecular approach to control functions of neural cells in epilepsy, depression and tumors of the central nervous system.American journal of cancer research · 2018Review
- Rewiring brain circuits to block cataplexy in murine models of narcolepsy.Current opinion in neurobiology · 2017Review
- Synaptic Ensemble Underlying the Selection and Consolidation of Neuronal Circuits during Learning.Frontiers in neural circuits · 2017Review
- Automated, highly reproducible, wide-field, light-based cortical mapping method using a commercial stereo microscope and its applications.Biomedical optics express · 2016Article
- Article
- Reorganization of Visual Callosal Connections Following Alterations of Retinal Input and Brain Damage.Frontiers in systems neuroscience · 2016Review
- Probing Neural Transplant Networks In Vivo with Optogenetics and Optogenetic fMRI.Stem cells international · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The recent development of light-activated optogenetic probes allows for the identification and manipulation of specific neural populations and their connections in awake animals with unprecedented spatial and temporal precision. This review describes the use of optogenetic tools to investigate neurons and neural circuits in vivo. We describe the current panel of optogenetic probes, methods of targeting these probes to specific cell types in the nervous system, and strategies of photostimulating cells in awake, behaving animals. Finally, we survey the application of optogenetic tools to studying functional neuroanatomy, behavior and the etiology and treatment of various neurological disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.