ReviewCurrent opinion in microbiology2011
Regulatory circuits controlling enterococcal conjugation: lessons for functional genomics.
Review in Current opinion in microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 39 citations in OpenAlex.
- Insights into ecology, pathogenesis, and biofilm formation ofMicrobiology and molecular biology reviews : MMBR · 2025Review
- Pheromone Activity after Stimulation with Ampicillin in a Plasmid-FreeMicroorganisms · 2022Article
- RcgA and RcgR, Two Novel Proteins Involved in the Conjugative Transfer of Rhizobial Plasmids.mBio · 2022Article
- Multiple Layered Control of the Conjugation Process of theFrontiers in molecular biosciences · 2021Review
- Enterococcal Genetics.Microbiology spectrum · 2019Review
- Blending genomes: distributive conjugal transfer in mycobacteria, a sexier form of HGT.Molecular microbiology · 2018Review
- PrgU: a suppressor of sex pheromone toxicity in Enterococcus faecalis.Molecular microbiology · 2017Article
- Enterococcal Sex Pheromones: Evolutionary Pathways to Complex, Two-Signal Systems.Journal of bacteriology · 2016Review
- Bacterial Cell-Cell Communication in the Host via RRNPP Peptide-Binding Regulators.Frontiers in microbiology · 2016Review
- Killing of VRE Enterococcus faecalis by commensal strains: Evidence for evolution and accumulation of mobile elements in the absence of competition.Gut microbes · 2016Article
- A complex genetic switch involving overlapping divergent promoters and DNA looping regulates expression of conjugation genes of a gram-positive plasmid.PLoS genetics · 2014Article
- Mechanism and structure of the bacterial type IV secretion systems.Biochimica et biophysica acta · 2014Review
- Regulated proteolysis in bacterial development.FEMS microbiology reviews · 2014Review
- Negative feedback and transcriptional overshooting in a regulatory network for horizontal gene transfer.PLoS genetics · 2014Article
- Social behavior and decision making in bacterial conjugation.Frontiers in cellular and infection microbiology · 2014Review
- Function of site-2 proteases in bacteria and bacterial pathogens.Biochimica et biophysica acta · 2013Review
- Mobility of the native Bacillus subtilis conjugative plasmid pLS20 is regulated by intercellular signaling.PLoS genetics · 2013Article
- Redundant group a streptococcus signaling peptides exhibit unique activation potentials.Journal of bacteriology · 2013Article
- Article
- Enterococcus faecalis PrgJ, a VirB4-like ATPase, mediates pCF10 conjugative transfer through substrate binding.Journal of bacteriology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The regulatory system controlling pheromone-induced plasmid transfer in Enterococcus faecalis is the most thoroughly studied genetic system of this species. Transcription initiation from the target promoter is controlled by a pheromone receptor/repressor protein whose activity is determined by its interaction with two peptide signaling molecules that compete for the same binding site, but have opposing effects on the activity of the receptor protein. For the system to function as a sensitive and robust biological switch, several additional levels of post-transcriptional regulation are also required. Expression of important functions encoded within the enterococcal core genome may also be controlled by multilayered regulatory circuitry. The pheromone system may serve as a useful paradigm to guide comprehensive functional genomic analysis of E. faecalis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.