ArticleCurrent biology : CB2011
A sensory code for host seeking in parasitic nematodes.
Article in Current biology : CB, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 1 of them a synthesis that pooled it.
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Who cites it
94 citing papers in PubMed, 1 synthesis or guideline pooled it.
- FMRFamide-like peptides expand the behavioral repertoire of a densely connected nervous system.Proceedings of the National Academy of Sciences of the United States of America · 2017Pooled it
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- A host-derived volatile primes context-dependent foraging behavior in parasitic nematodes via a lysosome-associated neural pathway.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Harnessing entomopathogenic nematodes for sustainable pest management: mechanisms, challenges, and innovations.Frontiers in plant science · 2026Review
- Nictation behavior in nematodes.BMC biology · 2025Review
- Evolution of lateralized gustation in nematodes.eLife · 2025Article
- Structural Diversity of Mitochondria in the Neuromuscular System across Development Revealed by 3D Electron Microscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Reversible kink instability drives ultrafast jumping in nematodes and soft robots.Science robotics · 2025Article
- Carbon dioxide shapes parasite-host interactions in a human-infective nematode.Current biology : CB · 2025Article
- Scent of death: Emission and behavioral role of 1-nonene in entomopathogenic nematode Steinernema kraussei.PloS one · 2025Article
- Carbon dioxide shapes parasite-host interactions in a human-infective nematode.bioRxiv : the preprint server for biology · 2024Article
- Dauer juvenile recovery transcriptome of two contrasting EMS mutants of the entomopathogenic nematode Heterorhabditis bacteriophora.World journal of microbiology & biotechnology · 2024Article
- Comparative connectomics of dauer reveals developmental plasticity.Nature communications · 2024Article
- Distinct neurogenetic mechanisms establish the same chemosensory valence state at different life stages in Caenorhabditis elegans.G3 (Bethesda, Md.) · 2024Article
- To live free or being a parasite: The optimal foraging behavior may favor the evolution of entomopathogenic nematodes.PloS one · 2024Article
- Chemotaxis ofMicroorganisms · 2023Article
- Article
- Differential processing of a chemosensory cue across life stages sharing the same valence state inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- StringentJournal of nematology · 2023Article
- Article
34 more citing papers are in PubMed but not listed here.
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7 authors.
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Abstract
Parasitic nematode species often display highly specialized host-seeking behaviors that reflect their specific host preferences. Many such behaviors are triggered by host odors, but little is known about either the specific olfactory cues that trigger these behaviors or the underlying neural circuits. Heterorhabditis bacteriophora and Steinernema carpocapsae are phylogenetically distant insect-parasitic nematodes whose host-seeking and host-invasion behavior resembles that of some devastating human- and plant-parasitic nematodes. We compare the olfactory responses of Heterorhabditis and Steinernema infective juveniles (IJs) to those of Caenorhabditis elegans dauers, which are analogous life stages. The broad host range of these parasites results from their ability to respond to the universally produced signal carbon dioxide (CO(2)), as well as a wide array of odors, including host-specific odors that we identified using thermal desorption-gas chromatography-mass spectroscopy. We find that CO(2) is attractive for the parasitic IJs and C. elegans dauers despite being repulsive for C. elegans adults, and we identify a sensory neuron that mediates CO(2) response in both parasitic and free-living species, regardless of whether CO(2) is attractive or repulsive. The parasites' odor response profiles are more similar to each other than to that of C. elegans despite their greater phylogenetic distance, likely reflecting evolutionary convergence to insect parasitism.
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