Evidence map›Paper›PMID 21350708›Full record

ReviewWorld journal of gastroenterology2011

Haemostatic system in inflammatory bowel diseases: new players in gut inflammation.

Franco Scaldaferri, Stefano Lancellotti, Marco Pizzoferrato, Raimondo De Cristofaro

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 54 citations in OpenAlex.

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  16. Risk of cardiovascular disease in inflammatory bowel disease.Experimental and therapeutic medicine · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Franco ScaldaferriDepartment of Internal Medicine and Medical Specialties, Gastroenterology Division, Catholic University of Rome, 00168 Rome, Italy.
Stefano Lancellotti
Marco Pizzoferrato
Raimondo De Cristofaro
Catholic University of America · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and coagulation constantly influence each other and are constantly in balance. Emerging evidence supports this statement in acute inflammatory diseases, such as sepsis, but it also seems to be very important in chronic inflammatory settings, such as inflammatory bowel disease (IBD). Patients with Crohn's disease and ulcerative colitis have an increased risk of thromboembolic events, and several abnormalities concerning coagulation components occur in the endothelial cells of intestinal vessels, where most severe inflammatory abnormalities occur. The aims of this review are to update and classify the type of coagulation system abnormalities in IBD, and analyze the strict and delicate balance between coagulation and inflammation at the mucosal level. Recent studies on possible therapeutic applications arising from investigations on coagulation abnormalities associated with IBD pathogenesis will also be briefly presented and critically reviewed.

Indexed as

HemostasisBlood CoagulationBlood Coagulation DisordersEndothelium, VascularGastrointestinal TractHumansInflammationInflammatory Bowel DiseasesThrombinThrombinActivated protein CCoagulationCrohn’s diseaseInflammationInflammatory bowel diseasePlateletsUlcerative colitis

Identifiers

PMID21350708
PMCPMC3040331
OpenAlexW1978857973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.