ReviewNutrients2011
Vitamin A metabolism: an update.
Review in Nutrients, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 258 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
258 citing papers in PubMed, 3 syntheses or guidelines pooled it, 537 citations in OpenAlex.
- Selected laboratory-based biomarkers for assessing vitamin A deficiency in at-risk individuals.The Cochrane database of systematic reviews · 2025Pooled it
- Pooled it
- Metabolism of Neonatal Vitamin A Supplementation: A Systematic Review.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Vitamins A, D, E, and K Intakes, Status, and Breastmilk Concentrations in Breastfeeding Women in Ireland.The Journal of nutrition · 2026Trial
- Role of vitamin A metabolism in IIH: Results from the idiopathic intracranial hypertension treatment trial.Journal of the neurological sciences · 2017Trial
- Revisiting retinoic acid in AML therapy: mechanisms of action and rational combination strategies.British journal of cancer · 2026Review
- Effect of Dietary Vitamin A, Breed, and Kidney Function on the Onset of Urinary Vitamin A Excretion and the Vitamin A Transport Complex in Growing Dogs.Journal of animal physiology and animal nutrition · 2026Article
- Assessment of genomic instability using the CBMN cytome assay in mother-newborn pairs prenatally exposed to pesticides in Colombia.Toxicology reports · 2026Article
- Bioengineered algal lipids enriched in structured medium- and long-chain triacylglycerols, linoleate, andbioRxiv : the preprint server for biology · 2026Article
- New Mechanistic Evidence for Perfluorodecanoic Acid (PFDA) Teratogenicity via CYP26A1-Mediated Retinoic Acid Metabolism and Signaling.Chemical research in toxicology · 2026Article
- Single-cell analysis of heterogeneity in reverted hiPSC-derived human hepatic stellate cells.JHEP reports : innovation in hepatology · 2026Article
- Association of maternal serum vitamin a levels in the first trimester with the risk of adverse pregnancy outcomes: a prospective cohort study of Chinese women.Frontiers in nutrition · 2026Article
- Bioactive Lipophilic Antioxidants (Carotenoids, Tocols, Retinol, and Coenzyme QAntioxidants (Basel, Switzerland) · 2025Article
- Sex differences of β-carotene effects in azoxymethane/dextran sulfate sodium-induced early colorectal cancer mice.Nutrition research and practice · 2025Article
- Review
- Prevalence and clinical impact of Vitamin A Deficiency (VAD) in critically ill children with sepsis.BMC pediatrics · 2025Article
- Perinatal vitamin A excess impacts vitamin A and lipid metabolism in rat offspring.Scientific reports · 2025Article
- Retinoid dynamics in vision: from visual cycle biology to retina disease treatments.Pharmacology & therapeutics · 2025Review
- Anti-DNA Damage Mechanisms and the Role of Carotenoids, Vitamin A, and Its Derivatives.Nutrients · 2025Review
- The Role of Lipid Metabolic Reprogramming in the Hibernation of Chipmunks.Animals : an open access journal from MDPI · 2025Article
198 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Retinoids are required for maintaining many essential physiological processes in the body, including normal growth and development, normal vision, a healthy immune system, normal reproduction, and healthy skin and barrier functions. In excess of 500 genes are thought to be regulated by retinoic acid. 11-cis-retinal serves as the visual chromophore in vision. The body must acquire retinoid from the diet in order to maintain these essential physiological processes. Retinoid metabolism is complex and involves many different retinoid forms, including retinyl esters, retinol, retinal, retinoic acid and oxidized and conjugated metabolites of both retinol and retinoic acid. In addition, retinoid metabolism involves many carrier proteins and enzymes that are specific to retinoid metabolism, as well as other proteins which may be involved in mediating also triglyceride and/or cholesterol metabolism. This review will focus on recent advances for understanding retinoid metabolism that have taken place in the last ten to fifteen years.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.