ArticleIndian journal of ophthalmology
Management of optic neuritis.
Article in Indian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 56 citations in OpenAlex.
- Visual Functions in Patients with Optic Neuritis Pre and Post Treatment: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Treatment and Relapse Prevention of Typical and Atypical Optic Neuritis.International journal of molecular sciences · 2022Review
- Clinico-epidemiologic characteristics of optic neuritis in a tertiary eye centre in Eastern India based on the status of serum aquaporin-4 antibody.Indian journal of ophthalmology · 2022Article
- Acute bilateral retrobulbar optic neuritis - An atypical sequela of COVID-19.Indian journal of ophthalmology · 2021Article
- The effect of optic neuritis treatment trial (ONTT) combined corticosteroid regimen on pattern reversal visual evoked potentials: a prospective follow-up study.BMC ophthalmology · 2021Observational
- Approach to optic neuritis: An update.Indian journal of ophthalmology · 2021Review
- Presumed herpes simplex virus endotheliitis following ultra-thin Descemet's stripping automated endothelial keratoplasty.Indian journal of ophthalmology · 2021Article
- Article
- Baseline Brain Activity Changes in Patients With Single and Relapsing Optic Neuritis.Frontiers in human neuroscience · 2018Article
- Optic neuritis as an early sign of multiple sclerosis.Eye and brain · 2016Review
- Optic neuritis as first clinical manifestations the multiple sclerosis.Materia socio-medica · 2014Article
- More about retinal disorders.Indian journal of ophthalmology · 2014Article
- Encephalitis followed by optic neuritis: a case report and review of literature.Pakistan journal of medical sciences · 2013Article
- Primary Sjögren's syndrome related optic neuritis.International journal of ophthalmology · 2013Article
- Optic neuritis, its differential diagnosis and management.The open ophthalmology journal · 2012Article
- Clinical spectrum of first episode of optic neuritis in a tertiary care hospital in Southern India - A retrospective analysis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optic neuritis is an inflammatory condition of the optic nerve characterized by a sudden onset of unilateral visual loss, usually affecting young females. Demyelination associated with multiple sclerosis (MS) is the most common cause in regions where MS is prevalent; while in other places, there are a substantial proportion of cases where infective or autoimmune causes are seen. Optic Neuritis Treatment Trial (ONTT) was the first major study that provided information on the natural history, role of steroids in treatment and risk of development of MS. Subsequently, numerous clinical trials have evaluated different modalities of management of optic neuritis and MS. The Controlled High-Risk Subjects Avonex Multiple Sclerosis Prevention Study (CHAMPS); the Prevention of Relapses and Disability by Interferon β-1a Subcutaneously in Multiple Sclerosis (PRISMS) Trial; and, most recently, the Betaferon in Newly Emerging Multiple Sclerosis for Initial Treatment (BENEFIT) Study have provided large amount of information on the natural history of optic neuritis and management options available. However, due to the low prevalence of MS reported in Asian studies, high cost of therapy and indefinite time period of treatment, it may not be cost effective to start interferon therapy in most cases.
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