ReviewPain management nursing : official journal of the American Society of Pain Management Nurses2011
Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders.
Review in Pain management nursing : official journal of the American Society of Pain Management Nurses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05495594 (Central Sensitization and Releated Factors in Medical Students), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Central Sensitization and Releated Factors in Medical Students: a Cross-Sectional Study
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evaluation of Central Sensitisation in Bladder Pain Syndrome: A Systematic Review.International urogynecology journal · 2024Pooled it
- Spinal manipulative therapy-specific changes in pain sensitivity in individuals with low back pain (NCT01168999).The journal of pain · 2014Trial
- A pilot study of myofascial release therapy compared to Swedish massage in fibromyalgia.Journal of bodywork and movement therapies · 2013Trial
- Expanding the Spectrum of Central Sensitivity Syndrome: Integrating Otologic Migraine as Otologic Central Sensitivity Syndrome.Brain sciences · 2026Review
- Chronic Overlapping Pain and Central Sensitization in Chronic Pelvic Pain: Do Positive and Negative Affect Play a Role?Pain research & management · 2026Article
- Nociplastic Pain: A Contemporary Narrative Review of Mechanisms, Clinical Assessment, Controversies, and Management.Journal of pain research · 2026Review
- Autistic women report high levels of pain, pain-related anxiety, and pain interference.Pain reports · 2025Article
- Investigating the Association Between Central Sensitization and Breathing Pattern Disorders.Biomedicines · 2025Article
- Small Fibre Pathology in Fibromyalgia: A review.Pain and therapy · 2025Review
- Laryngeal and Global Somatosensation in Primary Muscle Tension Dysphonia.Journal of voice : official journal of the Voice Foundation · 2024Article
- Night time heart rate predicts next-day pain in fibromyalgia and primary back pain.Pain reports · 2024Article
- Chronic nonspecific multiple-sites pain [CNMSP] of unknown etiology: Biopsychosocial method of evaluation for the primary care level.Journal of family medicine and primary care · 2024Article
- Exercise-induced hypoalgesia in chronic neck pain: A narrative review.Sports medicine and health science · 2024Review
- A Pilot Study of Functional Brain Magnetic Resonance Imaging in BPS/IC Patients: Evidence of Central Sensitization.Urology research & practice · 2024Article
- The Central Sensitization Inventory Measures Thoughts and Emotions.Journal of patient experience · 2024Article
- Pain in Adolescence: Maternal and Paternal Factors Affecting Adolescents' Pain in Norway-A Cross-Sectional Study.Children (Basel, Switzerland) · 2023Article
- DC/TMD Axis I diagnostic subtypes in TMD patients from Confucian heritage cultures: a stratified reporting framework.Clinical oral investigations · 2023Article
- Central Pain Sensitization in Patients with Chronic Plaque Psoriasis.Dermatology and therapy · 2023Article
- Feasibility, Acceptability, and Efficacy of Home-Based Transcranial Direct Current Stimulation on Pain in Older Adults with Alzheimer's Disease and Related Dementias: A Randomized Sham-Controlled Pilot Clinical Trial.Journal of clinical medicine · 2023Article
- Validity Testing of the Head and Neck Lymphedema and Fibrosis Symptom Inventory.Lymphatic research and biology · 2022Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The aim of this study was to review emerging data from the fields of nursing, rheumatology, dentistry, gastroenterology, gynecology, neurology, and orthopedics that support or dispute pathophysiologic similarities in pain syndromes studied by each specialty. A literature search was performed through PubMed and Ovid using the terms fibromyalgia, temporomandibular joint disorder, irritable bowel syndrome, irritable bladder/interstitial cystitis, headache, chronic low back pain, chronic neck pain, functional syndromes, and somatization. Each term was linked with pathophysiology and/or central sensitization. This paper presents a review of relevant articles with a specific goal of identifying pathophysiologic findings related to nociceptive processing. The extant literature presents considerable overlap in the pathophysiology of these diagnoses. Given the psychosomatic lens through which many of these disorders are viewed, demonstration of evidence-based links supporting shared pathophysiology between these disorders could provide direction to clinicians and researchers working to treat these diagnoses. "Central sensitivity syndromes" denotes an emerging nomenclature that could be embraced by researchers investigating each of these disorders. Moreover, a shared paradigm would be useful in promoting cross-fertilization between researchers. Scientists and clinicians could most effectively forward the understanding and treatment of fibromyalgia and other common chronic pain disorders through an appreciation of their shared pathophysiology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.