Evidence map›Paper›PMID 21349277›Full record

ReviewNeuropharmacology2012

Executive function and PTSD: disengaging from trauma.

Robin L Aupperle, Andrew J Melrose, Murray B Stein, Martin P Paulus

2 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neuropharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 284 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
284citing papers in PubMed, 9 pooled it
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02615717 nacompletednot on this mapstarted 2015, after this paper: background citation

Using Attentional Bias Modification to Address Trauma Symptoms

TypeinterventionalSponsorUniversity of Nebraska LincolnRan2015 to 2016Enrolled6ConditionsPosttraumatic Stress DisorderArmsAttention Bias Modification
NCT04076839 nacompletednot on this mapstarted 2017, after this paper: background citation

The Effectiveness of a Cognitive Training Program, Goal Management Training, on Reducing Cognitive Difficulties and Improving Every-day Functioning in Individuals With Affective Disorders

TypeinterventionalSponsorHomewood Research InstituteRan2017 to 2019Enrolled48ConditionsPost-traumatic Stress Disorder, Cognitive DysfunctionArmsGoal Management Training
3 · Its place in the literature

Who cites it

284 citing papers in PubMed, 9 syntheses or guidelines pooled it, 644 citations in OpenAlex.

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224 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Robin L AupperleDepartment of Psychiatry, University of California, San Diego (UCSD), 8939 Villa La Jolla Dr., Suite 200, La Jolla, CA 92037, USA. raupperle@ucsd.edu
Andrew J Melrose
Murray B Stein
Martin P Paulus
University of California, San Diego · US

Funding

NEUROBIOLOGY OF TRANSITION TO STIMULANT DEPENDENCER01DA016663 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PAULUS, MARTIN P. · 2004 to 2010
$2.8M
NIDA NIH HHS R01 DA016663
6 · The paper itself

Abstract

Neuropsychological approaches represent an important avenue for identifying susceptibility and resiliency factors relating to the development and maintenance of posttraumatic stress disorder (PTSD) symptoms post-trauma. This review will summarize results from prospective longitudinal and retrospective cross-sectional studies investigating executive function associated with PTSD. This research points specifically towards subtle impairments in response inhibition and attention regulation that may predate trauma exposure, serve as risk factors for the development of PTSD, and relate to the severity of symptoms. These impairments may be exacerbated within emotional or trauma-related contexts, and may relate to dysfunction within dorsal prefrontal networks. A model is presented concerning how such impairments may contribute to the clinical profile of PTSD and lead to the use of alternative coping styles such as avoidance. Further neuropsychological research is needed to identify the effects of treatment on cognitive function and to potentially characterize mechanisms of current PTSD treatments. Knowledge gained from cognitive and neuroscientific research may prove valuable for informing the future development of novel, more effective, treatments for PTSD. This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'.

Indexed as

Adaptation, PsychologicalAttentionExecutive FunctionHumansInhibition, PsychologicalMemory, Short-TermStress Disorders, Post-Traumatic

Identifiers

PMID21349277
PMCPMC4719148
OpenAlexW2106557234

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.