Evidence map›Paper›PMID 21348564›Full record

SynthesisThe American journal of managed care2010

Modes of delivery for interventions to improve cardiovascular medication adherence.

Sarah L Cutrona, Niteesh K Choudhry, Michael A Fischer, Amber Servi, Joshua N Liberman, Troyen A Brennan, William H Shrank

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in The American journal of managed care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05334446 (The Effect on Treatment Compliance and Self-Care Management in Patients With Hypertension), which is not on this map. Cited by 42 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05334446 nacompletednot on this mapstarted 2021, after this paper: background citation

The Effect on Treatment Compliance and Self-Care Management in Patients With Hypertension

TypeinterventionalSponsorSelcuk UniversityRan2021 to 2022Enrolled33ConditionsHypertensionArmsThe Effect of the Mobile Application
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  4. Technology-mediated interventions for enhancing medication adherence.Journal of the American Medical Informatics Association : JAMIA · 2015
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Sarah L CutronaDivision of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, USA. slcutrona@gmail.com
Niteesh K Choudhry
Michael A Fischer
Amber Servi
Joshua N Liberman
Troyen A Brennan
William H Shrank

Funding

An intervention to improve rational prescribing in cardiovascular diseaseK23HL090505 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SHRANK, WILLIAM · 2007 to 2010
$650k
NHLBI NIH HHS HL-090505NHLBI NIH HHS K23 HL090505
6 · The paper itself

Abstract

objectiveTo determine the optimal modes of delivery for interventions to improve adherence to cardiovascular medications. STUDY

designSystematic review.

methodsWe conducted systematic searches of English-language, peer-reviewed publications in MEDLINE and EMBASE, 1966 through December 31, 2008. We selected randomized controlled trials of interventions to improve adherence to medications for preventing or treating cardiovascular disease or diabetes. Articles were classified based on mode of delivery of the main intervention as (1) person-independent interventions (mailed, faxed, or hand distributed; or delivered via electronic interface) or (2) person-dependent interventions (nonautomated phone calls, in-person interventions).

resultsWe identified 6550 articles. Of these, 168 were reviewed in full and 51 met inclusion criteria. Among person-independent interventions (56% successful), electronic interventions were most successful (67%). Among person-dependent interventions (52% successful), phone calls showed low success rates (38%). In-person interventions at hospital discharge were more effective (67%) than clinic interventions (47%). In-person pharmacist interventions were effective when held in a pharmacy (83% successful), but were less effective in clinics (38%).

conclusionsFuture medication adherence studies should explore new electronic approaches and in-person interventions at the site of medication distribution. Identifying times of increased patient receptivity to the adherence message such as hospital discharge also will be important.

Indexed as

Drug MonitoringPrescription DrugsAntihypertensive AgentsCardiovascular DiseasesCommunicationDiabetes MellitusDirective CounselingHumansHypoglycemic AgentsPatient DischargePatient Education as TopicPharmaciesProfessional-Patient RelationsTelephoneUnited StatesAntihypertensive AgentsHypoglycemic AgentsPrescription Drugs

Identifiers

PMID21348564
PMCPMC3115758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.