ArticlePloS one2011
Differential consolidation and pattern reverberations within episodic cell assemblies in the mouse hippocampus.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Impact of Impedance Levels on Recording Quality in Flexible Neural Probes.Sensors (Basel, Switzerland) · 2024Article
- Large-Scale Circuitry Interactions Upon Earthquake Experiences Revealed by Recurrent Neural Networks.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2018Article
- 512-Channel and 13-Region Simultaneous Recordings Coupled with Optogenetic Manipulation in Freely Behaving Mice.Frontiers in systems neuroscience · 2016Article
- Theory of Connectivity: Nature and Nurture of Cell Assemblies and Cognitive Computation.Frontiers in neural circuits · 2016Article
- The Minimal k-Core Problem for Modeling k-Assemblies.Journal of mathematical neuroscience · 2015Article
- Article
- On initial Brain Activity Mapping of episodic and semantic memory code in the hippocampus.Neurobiology of learning and memory · 2013Review
- Special issue on consolidation, reconsolidation and extinction.Psychopharmacology · 2013Article
- Mapping and deciphering neural codes of NMDA receptor-dependent fear memory engrams in the hippocampus.PloS one · 2013Article
- Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory.Scientific reports · 2013Article
- NMDA receptors are not required for pattern completion during associative memory recall.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
One hallmark feature of consolidation of episodic memory is that only a fraction of original information, which is usually in a more abstract form, is selected for long-term memory storage. How does the brain perform these differential memory consolidations? To investigate the neural network mechanism that governs this selective consolidation process, we use a set of distinct fearful events to study if and how hippocampal CA1 cells engage in selective memory encoding and consolidation. We show that these distinct episodes activate a unique assembly of CA1 episodic cells, or neural cliques, whose response-selectivity ranges from general-to-specific features. A series of parametric analyses further reveal that post-learning CA1 episodic pattern replays or reverberations are mostly mediated by cells exhibiting event intensity-invariant responses, not by the intensity-sensitive cells. More importantly, reactivation cross-correlations displayed by intensity-invariant cells encoding general episodic features during immediate post-learning period tend to be stronger than those displayed by invariant cells encoding specific features. These differential reactivations within the CA1 episodic cell populations can thus provide the hippocampus with a selection mechanism to consolidate preferentially more generalized knowledge for long-term memory storage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.