Evidence map›Paper›PMID 21347209›Full record

ArticleThe open neurology journal2010

Supratentorial multiple sclerosis lesions affect the blink reflex test.

Efthimios H Mikropoulos, Afroditi A Papathanasiou, Georgios Hadjigeorgiou, Evangelia Tsironi, Alex Papadimitriou

Open access · hybridAbstract read
In one paragraph

Article in The open neurology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Efthimios H MikropoulosDepartment of Neurology, Faculty of Medicine, School of Health Sciences, University of Thessaly, P.O. Box 1400, Mezourlo Hill, Larissa, Greece.
Afroditi A Papathanasiou
Georgios Hadjigeorgiou
Evangelia Tsironi
Alex Papadimitriou
University of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Blink Reflex Test (BRT) is a neurophysiological examination used for evaluation of brainstem reflex circuits. MRI is the most precise modality for evaluation of MS lesion anatomy. Our study objective was to investigate how the functional results of the neurophysiological BRT relate to the anatomy of MS lesions in routine MRI studies.

methods65 MS patients underwent the BRT within 2 months of a brain MRI showing demyelinating lesions.

resultsThe overall sensitivity of the BRT was 90.8%, while in patients with at least one brainstem lesion and no brainstem lesions it was 91.4% and 90%, respectively. DISCUSSION: The presence of brainstem lesions does not significantly affect BRT sensitivity. This points to the influence of supratentorial MS lesions on the BRT. Gender, age, disease duration, type of MS, acuteness of an MS event and whether MS diagnosis was recent or not were not variables affecting the results.

Indexed as

Blink Reflex TestBrainstem.MRI BrainMultiple SclerosisSupratentorial Lesions

Identifiers

PMID21347209
PMCPMC3043265
OpenAlexW2165147211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.