Evidence map›Paper›PMID 21347044›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2010

Enabling Hierarchical View of RxNorm with NDF-RT Drug Classes.

Matvey B Palchuk, Michael Klumpenaar, Tarang Jatkar, Ralph J Zottola, William G Adams, Aaron H Abend

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Standardizing adverse drug event reporting data.Journal of biomedical semantics · 2014
    Article
  6. Use of RxNorm and NDF-RT to normalize and characterize participant-reported medications in an i2b2-based research repository.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2014
    Article
  7. Evaluation of RxNorm for Medication Clinical Decision Support.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2014
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Integrating VA's NDF-RT drug terminology with PharmGKB: preliminary results.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2012
    Article
  13. Further revamping VA's NDF-RT drug terminology for clinical research.Journal of the American Medical Informatics Association : JAMIA · 2011
    Article
  14. Article
  15. Evaluating standard terminologies for encoding allergy information.Journal of the American Medical Informatics Association : JAMIA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matvey B PalchukRecombinant Data Corp., Newton, MA;
Michael Klumpenaar
Tarang Jatkar
Ralph J Zottola
William G Adams
Aaron H Abend

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NDF-RT is the proposed source of drug classification information. We set out to construct a hierarchy of NDF-RT drug classes and RxNorm medications and evaluate it on medication records data. NDF-RT and RxNorm are distributed in different file formats, require different tools to manipulate and linking the two into a hierarchy is a non-trivial exercise. Medication data in RxNorm from two institutions was constrained by the hierarchy. Only 37% of records from one and 65% from another institution were accessible. We subsequently enriched the RxNorm mapping in NDF-RT by exploiting relationships between concepts for branded and generic drugs. Coverage improved dramatically to 93% for both institutions. To improve usability of the resulting hierarchy, we grouped clinical drugs by corresponding clinical drug form.

Indexed as

RxNormVocabulary, ControlledHumansPharmaceutical PreparationsPharmaceutical Preparations

Identifiers

PMID21347044
PMCPMC3041416

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.