Evidence map›Paper›PMID 21346044›Full record

ArticleJournal of clinical microbiology2011

Streptococcus pneumoniae isolates from middle ear fluid and nasopharynx of children with acute otitis media exhibit phase variation.

Jun Arai, Muneki Hotomi, Susan K Hollingshead, Yumi Ueno, David E Briles, Noboru Yamanaka

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Carbon source-dependent capsule thickness regulation inFrontiers in cellular and infection microbiology · 2023
    Article
  3. Population structure of ocularMicrobial genomics · 2022
    Article
  4. Article
  5. Comparative Analysis ofPathogens (Basel, Switzerland) · 2020
    Article
  6. Article
  7. Article
  8. Review
  9. Phase Variation ofMicrobiology spectrum · 2019
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Understanding the pneumococcus: transmission and evolution.Frontiers in cellular and infection microbiology · 2013
    Review
  17. Article
  18. Article
  19. Article
  20. mSphere
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun AraiDepartment of Otolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
Muneki Hotomi
Susan K Hollingshead
Yumi Ueno
David E Briles
Noboru Yamanaka

Funding

NIAID NIH HHS AI021458
6 · The paper itself

Abstract

Pneumococcal phase variation of 37 middle ear and 31 nasopharyngeal isolates obtained from children with acute otitis media was examined in the absence of intervening culture. The fraction of the opaque colonies was significantly higher in middle ear isolates than in nasopharyngeal isolates. The difference is probably the result of the pneumococci adapting to differential selective environments.

Indexed as

Antigens, BacterialCarrier StateEar, MiddleFemaleGenetic VariationHumansInfantMaleNasopharynxOtitis MediaPneumococcal InfectionsStreptococcus pneumoniaeAntigens, Bacterial

Identifiers

PMID21346044
PMCPMC3122802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.