ArticleTrends in parasitology2011
Malaria and trypanosome transmission: different parasites, same rules?
Article in Trends in parasitology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transfusion-transmitted malaria in sub-Saharan Africa: a systematic review and meta-analysis of Plasmodium spp. carriage in blood units and confirmed transmission in recipient.Malaria journal · 2026Pooled it
- DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cells.PLoS pathogens · 2013Trial
- Five-Year Experience of the Groupe de Recherche Action en Santé (GRAS) Clinical Laboratory, Burkina Faso, in Participating into an External Proficiency Testing (EPT) Programme.Diagnostics (Basel, Switzerland) · 2025Article
- Antiprotozoal Aminosteroids fromMolecules (Basel, Switzerland) · 2025Article
- A sticky situation: When trypanosomatids attach to insect tissues.PLoS pathogens · 2023Review
- Double trouble: trypanosomatids with two hosts have lower infection prevalence than single host trypanosomatids.Evolution, medicine, and public health · 2023Article
- Bacteriocins: Potential for Human Health.Oxidative medicine and cellular longevity · 2021Review
- Inhibition ofJournal of experimental pharmacology · 2019Article
- Linked within-host and between-host models and data for infectious diseases: a systematic review.PeerJ · 2019Article
- Phenotypic plasticity in reproductive effort: malaria parasites respond to resource availability.Proceedings. Biological sciences · 2017Article
- Article
- Review
- Kin Discrimination in Protists: From Many Cells to Single Cells and Backwards.The Journal of eukaryotic microbiology · 2016Article
- Molecular control of irreversible bistability during trypanosome developmental commitment.The Journal of cell biology · 2015Article
- Article
- Evidence of Taxa-, Clone-, and Kin-discrimination in Protists: Ecological and Evolutionary Implications.Evolutionary ecology · 2014Article
- Information use and plasticity in the reproductive decisions of malaria parasites.Malaria journal · 2014Article
- Trypanosomes genetic diversity, polyparasitism and the population decline of the critically endangered Australian marsupial, the brush tailed bettong or woylie (Bettongia penicillata).International journal for parasitology. Parasites and wildlife · 2013Article
- Plasticity in transmission strategies of the malaria parasite, Plasmodium chabaudi: environmental and genetic effects.Evolutionary applications · 2013Article
- Stress and sex in malaria parasites: Why does commitment vary?Evolution, medicine, and public health · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
African trypanosomes produce different specialized stages for within-host replication and between-host transmission and therefore face a resource allocation trade-off between maintaining the current infection (survival) and investment into transmission (reproduction). Evolutionary theory predicts the resolution of this trade-off will significantly affect virulence and infectiousness. The application of life history theory to malaria parasites has provided novel insight into their strategies for survival and reproduction; how this framework can now be applied to trypanosomes is discussed. Specifically, predictions for how parasites trade-off investment in survival and transmission in response to variation in the within-host environment are outlined. An evolutionary approach has the power to explain why patterns of investment vary between strains and during infections, giving important insights into parasite biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.