ArticlePlanta2011
The fatal effect of tungsten on Pisum sativum L. root cells: indications for endoplasmic reticulum stress-induced programmed cell death.
Article in Planta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 49 citations in OpenAlex.
- Ecotoxicological effects of tungsten on celery (PeerJ · 2024Article
- Article
- Autophagy-an underestimated coordinator of construction and destruction during plant root ontogeny.Planta · 2021Review
- Review
- Concentration-dependent effects of tungstate on germination, growth, lignification-related enzymes, antioxidants, and reactive oxygen species in broccoli (Brassica oleracea var. italica L.).Environmental science and pollution research international · 2019Article
- Copper treatment of peach leaves causes lesion formation similar to the biotic stress response.Plant biotechnology (Tokyo, Japan) · 2019Article
- Structural Evidence of Programmed Cell Death Induction by Tungsten in Root Tip Cells ofPlants (Basel, Switzerland) · 2019Article
- Ethylene modulates root cortical senescence in barley.Annals of botany · 2018Article
- Responses of Plant Proteins to Heavy Metal Stress-A Review.Frontiers in plant science · 2017Review
- Endoplasmic Reticulum Stress Response in Arabidopsis Roots.Frontiers in plant science · 2017Article
- Hop/Sti1 - A Two-Faced Cochaperone Involved in Pattern Recognition Receptor Maturation and Viral Infection.Frontiers in plant science · 2017Article
- Comparison of antioxidant enzyme activities and DNA damage in chickpea (Cicer arietinum L.) genotypes exposed to vanadium.Environmental science and pollution research international · 2016Article
- Early generation of nitric oxide contributes to copper tolerance through reducing oxidative stress and cell death in hulless barley roots.Journal of plant research · 2016Article
- Elemental composition of Marrubium astracanicum Jacq. growing in tungsten-contaminated sites.Environmental science and pollution research international · 2016Article
- Hexavalent chromium-induced differential disruption of cortical microtubules in some Fabaceae species is correlated with acetylation of α-tubulin.Protoplasma · 2016Article
- Seed birth to death: dual functions of reactive oxygen species in seed physiology.Annals of botany · 2015Review
- Chromium-Induced Ultrastructural Changes and Oxidative Stress in Roots of Arabidopsis thaliana.International journal of molecular sciences · 2015Article
- Aberration of mitosis by hexavalent chromium in some Fabaceae members is mediated by species-specific microtubule disruption.Environmental science and pollution research international · 2015Article
- ROS-mediated abiotic stress-induced programmed cell death in plants.Frontiers in plant science · 2015Review
- The nitrate reductase inhibitor, tungsten, disrupts actin microfilaments in Zea mays L.Protoplasma · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Programmed cell death (PCD) is a widespread response of plants against abiotic stress, such as heavy metal toxicity. Tungsten (W) is increasingly considered toxic for plants since it irreversibly affects their growth. Therefore, we investigated whether W could induce some kind of PCD in plants, like other heavy metals do. The morphology of cell and nucleus, the integrity of the cytoskeleton, Evans Blue absorbance and the expression of PCD-related genes were used as indicators of PCD in W-treated roots of Pisum sativum (pea). TEM and fluorescence microscopy revealed mitotic cycle arrest, protoplast shrinkage, disruption of the cytoskeleton and chromatin condensation and peripheral distribution in the nucleus of W-affected cells. Moreover, Evans Blue absorbance in roots increased in relation to the duration of W treatment. These effects were suppressed by inhibitors of the 26S proteasome, caspases and endoplasmic reticulum stress. In addition, silencing of DAD-1 and induction of HSR203J, BiP-D, bZIP28 and bZIP60 genes were also recorded in W-treated pea roots by semi-quantitative RT-PCR. The above observations show that W induces a kind of PCD in pea roots, further substantiating its toxicity for plants. Data imply that endoplasmic reticulum stress-unfolded protein response may be involved in W-induced PCD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.