ArticleNeuroradiology2012
Order of CT stroke protocol (CTA before or after CTP): impact on image quality.
Article in Neuroradiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Optimization of the Sequence of Computed Tomography Angiography and Perfusion in One-Stop-Shop CT Imaging for Acute Ischemic Stroke.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Contrast bolus timing in CT-angiography and CT-perfusion: insights from a large clinical dataset.Neuroradiology · 2025Article
- Reduction in Radiation Exposure of CT Perfusion by Optimized Imaging Timing Using Temporal Information of the Preceding CT Angiography of the Carotid Artery in the Stroke Protocol.Diagnostics (Basel, Switzerland) · 2022Article
- Angiography suite cone-beam CT perfusion for selection of thrombectomy patients: A pilot study.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
- Contrast Bolus Interference in a Multimodal CT Stroke Protocol.AJNR. American journal of neuroradiology · 2021Article
- Single rotation CTA of extracranial carotids integrated with cerebral CTP provides sufficient quality for decision making in patients with ischaemic stroke.The neuroradiology journal · 2021Article
- Recent Administration of Iodinated Contrast Renders Core Infarct Estimation Inaccurate Using RAPID Software.AJNR. American journal of neuroradiology · 2020Article
- Comparison of Renal Blood Flow Using Maximum Slope-Based Computed Tomography Perfusion and Ultrasound Flow Probe in Healthy Dogs.Frontiers in veterinary science · 2020Article
- Carotid artery stenting in a single center, single operator, single type of device and 15 years of follow-up.CVIR endovascular · 2018Article
- Feasibility of Flat Panel Detector CT in Perfusion Assessment of Brain Arteriovenous Malformations: Initial Clinical Experience.AJNR. American journal of neuroradiology · 2017Article
- Non-invasive assessment of vasospasm following aneurysmal SAH using C-arm FDCT parenchymal blood volume measurement in the neuro-interventional suite: Technical feasibility.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2015Article
- Quality of extracranial carotid evaluation with 256-section CT.AJNR. American journal of neuroradiology · 2013Article
- Differences in CT perfusion summary maps for patients with acute ischemic stroke generated by 2 software packages.AJNR. American journal of neuroradiology · 2012Article
- Hyperdense basilar artery sign-a reliable sign of basilar artery occlusion.Neuroradiology · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe purpose of this study was to determine the appropriate order of CT angiography and CT perfusion in a multimodal stroke CT protocol.
methodsForty patients with clinical suspicion of an acute cerebral infarct underwent non-enhanced CT (NECT), CT angiography (CTA), and CT perfusion (CTP). Twenty examinations were performed with CTP before CTA (group 1) and 20 in reversed order (group 2). Mean densities were determined at baseline and peak enhancement of CTP, as well as on source images of CTA in defined brain regions. Contrast of extra-/intracranial arteries and veins was rated according to a 5-point scale (1 = excellent, 5 = poor). CT-perfusion maps were assessed by determining the mean transit time (MTT), cerebral blood flow (CBF), and blood volume (CBV) in identical regions.
resultsMean densities between both groups were not significantly different for CTA and CTP at peak enhancement. At CTP baseline, mean densities between groups 1 and 2 were different for all points except for GM and WM. There was no significant difference between both groups for the mean delta (the difference between baseline and peak enhancement), as well as for mean MTT, CBV, and CBF. Subjective evaluation of the CTA quality revealed no difference between both protocols, except for the extracranial venous contrast, which was less severe in group 2.
conclusionReversal of CT stroke protocol had no significant influence on quantitative parameters of CTP. Subjective quality of extracranial venous contrast was rated to be superior when CTA was performed before CTP.
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