ArticleFrontiers in human neuroscience2011
Taking Sides with Pain - Lateralization aspects Related to Cerebral Processing of Dental Pain.
Article in Frontiers in human neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- A meta-analytic study of experimental and chronic orofacial pain excluding headache disorders.NeuroImage. Clinical · 2018Pooled it
- Being praised and criticized in adolescents and adults: Age-related changes in neural responses to social evaluations.Developmental cognitive neuroscience · 2026Article
- Increased Expression of TRPV1 in the Central Nucleus of the Amygdala Is Involved in Orthodontic Pain in Rats.International journal of molecular sciences · 2025Article
- Neurochemical dynamics during two hypnotic states evidenced by magnetic resonance spectroscopy.Scientific reports · 2024Article
- Neural Functioning in Late-Life Depression: An Activation Likelihood Estimation Meta-Analysis.Geriatrics (Basel, Switzerland) · 2024Review
- Pain-related cortico-limbic plasticity and opioid signaling.Neuropharmacology · 2023Review
- Frequency-Dependent Alterations in the Amplitude of Low-Frequency Fluctuations in Patients with Acute Pericoronitis: A Resting-State fMRI Study.Journal of pain research · 2023Article
- A nigro-subthalamo-parabrachial pathway modulates pain-like behaviors.Nature communications · 2022Article
- Altered regional homogeneity of spontaneous brain activity in patients with toothache: A resting-state functional magnetic resonance imaging study.Frontiers in neuroscience · 2022Article
- Resting-state functional heterogeneity of the right insula contributes to pain sensitivity.Scientific reports · 2021Article
- A lateralized model of the pain-depression dyad.Neuroscience and biobehavioral reviews · 2021Review
- Tracking local anesthetic effects using a novel perceptual reference approach.Journal of neurophysiology · 2016Article
- New Insights in Trigeminal Anatomy: A Double Orofacial Tract for Nociceptive Input.Frontiers in neuroanatomy · 2016Article
- Asymmetry of the endogenous opioid system in the human anterior cingulate: a putative molecular basis for lateralization of emotions and pain.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Fear avoidance beliefs in back pain-free subjects are reflected by amygdala-cingulate responses.Frontiers in human neuroscience · 2015Article
- Equal pain-Unequal fear response: enhanced susceptibility of tooth pain to fear conditioning.Frontiers in human neuroscience · 2014Article
- Differential NMR spectroscopy reactions of anterior/posterior and right/left insular subdivisions due to acute dental pain.European radiology · 2013Article
- Beta oscillations in the monkey sensorimotor network reflect somatosensory decision making.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current fMRI study investigated cortical processing of electrically induced painful tooth stimulation of both maxillary canines and central incisors in 21 healthy, right-handed volunteers. A constant current, 150% above tooth specific pain perception thresholds was applied and corresponding online ratings of perceived pain intensity were recorded with a computerized visual analog scale during fMRI measurements. Lateralization of cortical activations was investigated by a region of interest analysis. A wide cortical network distributed over several areas, typically described as the pain or nociceptive matrix, was activated on a conservative significance level. Distinct lateralization patterns of analyzed structures allow functional classification of the dental pain processing system. Namely, certain parts are activated independent of the stimulation site, and hence are interpreted to reflect cognitive emotional aspects. Other parts represent somatotopic processing and therefore reflect discriminative perceptive analysis. Of particular interest is the observed amygdala activity depending on the stimulated tooth that might indicate a role in somatotopic encoding.
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