ArticleNanotechnology2011
Synthesis and bioevaluation of ¹²⁵I-labeled gold nanorods.
Article in Nanotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 34 citations in OpenAlex.
- Direct Labeling of Gold Nanoparticles with Iodine-131 for Tumor Radionuclide Therapy.International journal of nanomedicine · 2024Article
- Preparation and Evaluation ofPharmaceuticals (Basel, Switzerland) · 2023Article
- Methods for Radiolabelling Nanoparticles: SPECT Use (Part 1).Biomolecules · 2022Review
- Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential asACS omega · 2019Article
- Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe.Nanotechnology · 2019Article
- Iron Oxide Nanoradiomaterials: Combining Nanoscale Properties with Radioisotopes for Enhanced Molecular Imaging.Contrast media & molecular imaging · 2017Review
- Article
- Chemisorption of iodine-125 to gold nanoparticles allows for real-time quantitation and potential use in nanomedicine.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2017Article
- Synthesis and Bioevaluation of Iodine-131 Directly Labeled Cyclic RGD-PEGylated Gold Nanorods for Tumor-Targeted Imaging.Contrast media & molecular imaging · 2017Article
- Quantitatively Understanding Cellular Uptake of Gold Nanoparticles via Radioactivity Analysis.Journal of nanoscience and nanotechnology · 2015Article
- Emerging role of radiolabeled nanoparticles as an effective diagnostic technique.EJNMMI research · 2012Article
- Regiospecific plasmonic assemblies for in situ Raman spectroscopy in live cells.Journal of the American Chemical Society · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
A novel technique is described for monitoring the in vivo behavior of gold nanorods (GNRs) using γ-imaging. GNRs were radiolabeled using [¹²⁵I] sodium iodide in a simple and fast manner with high yield and without disturbing their optical properties. Radiolabeled GNRs were successfully visualized by radioisotope tagging, allowing longitudinal in vivo studies to be performed repeatedly in the same animal. The preliminary biodistribution study showed that PEGylated GNRs have much longer blood circulation times and clear out faster, while bare GNRs accumulate quickly in the liver after systematic administration. The highly efficient method reported here provides an extensively useful tool for guidance of the design and development of new gold nanoparticles as target-specific agents for both diagnostics and photothermal therapy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.