Evidence map›Paper›PMID 21343452›Full record

ArticleAntimicrobial agents and chemotherapy2011

In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates.

Emilio Pérez-Trallero, Esther Tamayo, Milagrosa Montes, José M García-Arenzana, Victor Iriarte

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emilio Pérez-TralleroCIBERES, San Sebastián, Spain. mikrobiol@terra.es
Esther Tamayo
Milagrosa Montes
José M García-Arenzana
Victor Iriarte

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retapamulin in vitro activity against 400 Streptococcus pyogenes clinical isolates obtained from skin, pharynx, ear fluid, and blood samples recovered from 2007 to 2009 was studied. The isolates belonged to 26 different emm types, including isolates nonsusceptible to erythromycin (n=187), tetracycline (n=99), ciprofloxacin (n=59), and bacitracin (n=43). Results were compared to the activities of 16 other antibiotics for topical and systemic use. Retapamulin MICs ranged from ≤0.015 to 0.12 μg/ml, showing the highest intrinsic activity among the topical antimicrobial drugs studied.

Indexed as

Anti-Infective AgentsBacitracinBridged Bicyclo Compounds, HeterocyclicCiprofloxacinDiterpenesErythromycinMicrobial Sensitivity TestsStreptococcus pyogenesTetracyclineAnti-Infective AgentsBacitracinBridged Bicyclo Compounds, HeterocyclicCiprofloxacinDiterpenesErythromycinretapamulinTetracycline

Identifiers

PMID21343452
PMCPMC3088200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.