ArticleBiomedical optics express2011
Skeletal muscle sarcomeric SHG patterns photo-conversion by femtosecond infrared laser.
Article in Biomedical optics express, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 13 citations in OpenAlex.
- Determination of the source of SHG verniers in zebrafish skeletal muscle.Scientific reports · 2015Article
- Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation.Oxidative medicine and cellular longevity · 2015Article
- Myofibrillar misalignment correlated to triad disappearance of mdx mouse gastrocnemius muscle probed by SHG microscopy.Biomedical optics express · 2014Article
- Theoretical and experimental SHG angular intensity patterns from healthy and proteolysed muscles.Biophysical journal · 2013Article
- Imaging the bipolarity of myosin filaments with Interferometric Second Harmonic Generation microscopy.Biomedical optics express · 2013Article
- Article
- Modeling of supramolecular centrosymmetry effect on sarcomeric SHG intensity pattern of skeletal muscles.Biophysical journal · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Femtosecond laser at 780 nm excitation wavelength was used to photo-convert the physiological sarcomeric single band (SB) second harmonic generation (SHG) pattern into double band (DB) in Xenopus laevis premetamorphic tail muscles. This photo-conversion was found to be a third order non-linear optical process and was drastically reduced at 940 nm excitation wavelength. This effect was no longer observed in paraformaldehyde fixed muscles and was enhanced by hydrogen peroxide. The action of hydrogen peroxide suggests that reactive oxygen species (ROS) could contribute to this photo-conversion. These results demonstrate that sarcomeric DB SHG pattern is a marker of sarcomere photodamage in xenopus tadpole muscles and highlight the need of being very careful at using two-photon excitation while observing living tissues. Moreover they open new avenues for in situ intravital investigation of oxidative stress effects in muscle dysfunctions and diseases.
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Registered trials
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