Evidence map›Paper›PMID 21338880›Full record

ReviewNeuron2011

Neuroscience of behavioral and pharmacological treatments for addictions.

Marc N Potenza, Mehmet Sofuoglu, Kathleen M Carroll, Bruce J Rounsaville

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuron, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 6 pooled it
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 6 syntheses or guidelines pooled it, 215 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Food cue reactivity and craving predict eating and weight gain: a meta-analytic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2016
    Pooled it
  5. Neuroimaging craving: urge intensity matters.Addiction (Abingdon, England) · 2015
    Pooled it
  6. Pooled it
  7. Trial
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  10. Functional neural changes following behavioral therapies and disulfiram for cocaine dependence.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2017
    Trial
  11. Trial
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  14. Cannabis abstinence during treatment and one-year follow-up: relationship to neural activity in men.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2014
    Trial
  15. Trial
  16. Neurobiological considerations in understanding behavioral treatments for pathological gambling.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2013
    Trial
  17. Dorsolateral prefrontal and orbitofrontal cortex interactions during self-control of cigarette craving.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Trial
  18. Article
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Marc N PotenzaDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA. marc.potenza@yale.edu
Mehmet Sofuoglu
Kathleen M Carroll
Bruce J Rounsaville
Yale University · US

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
CLINICAL TRIALS NETWORK: NEW ENGLAND NODEU10DA013038 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1999 to 2010
$17.3M
Sex Differences in Stress Related RelapseP50DA016556 · NIDA · YALE UNIVERSITY · PI SINHA, RAJITA · 2002 to 2011
$10.4M
Behavioral Technologies for Predicting HIV RiskR01DA018647 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI LEJUEZ, CARL W · 2005 to 2014
$5.2M
Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2010 to 2013
$3.6M
Computer-Based Training in Cognitve Behavioral TherapyR01DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2002 to 2015
$2.8M
Computer-Based Training in Cognitve Behavioral TherapyR37DA015969 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 2003 to 2009
$2.6M
fMRI of CBT and CM for Cocaine DependenceR01DA020908 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2005 to 2009
$1.7M
fMRI of Craving in Addictions: Gender DifferencesR01DA019039 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2005 to 2009
$1.6M
Cognitive Enhancement as a Target for Cocaine PharmacotherapyR01DA029577 · NIDA · YALE UNIVERSITY · PI SOFUOGLU, MEHMET · 2011 to 2015
$1.5M
fMRI of Stress & Self-Control in Smoking & Obesity (7 of 14)RL1AA017539 · NIAAA · YALE UNIVERSITY · PI POTENZA, MARC N · 2007 to 2011
$1.3M
NIAAA NIH HHS RL1 AA017539NIAAA NIH HHS RL1-AA017539NIDA NIH HHS K02 DA021304NIDA NIH HHS K02-DA021304NIDA NIH HHS K05 DA000089NIDA NIH HHS K05 DA000457NIDA NIH HHS K12 DA000167NIDA NIH HHS P20 DA027844NIDA NIH HHS P20-DA027844NIDA NIH HHS P50 DA009241NIDA NIH HHS P50 DA016556NIDA NIH HHS P50-DA016556NIDA NIH HHS P50-DA09241NIDA NIH HHS R01 DA014537NIDA NIH HHS R01 DA015969NIDA NIH HHS R01 DA018647NIDA NIH HHS R01-DA018647NIDA NIH HHS R01 DA019039NIDA NIH HHS R01-DA019039NIDA NIH HHS R01 DA019885NIDA NIH HHS R01 DA020752NIDA NIH HHS R01 DA020908NIDA NIH HHS R01-DA020908NIDA NIH HHS R01 DA029577NIDA NIH HHS R21 DA029445NIDA NIH HHS R37 DA015969NIDA NIH HHS R37-DA015969NIDA NIH HHS RC1 DA028279NIDA NIH HHS RC1-DA028279NIDA NIH HHS U10 DA013038
6 · The paper itself

Abstract

Although substantial advances have been made in behavioral and pharmacological treatments for addictions, moving treatment development to the next stage may require novel ways of approaching addictions, particularly ways based on new findings regarding the neurobiological underpinnings of addictions that also assimilate and incorporate relevant information from earlier approaches. In this review, we first briefly review theoretical and biological models of addiction and then describe existing behavioral and pharmacologic therapies for the addictions within this framework. We then propose new directions for treatment development and targets that are informed by recent evidence regarding the heterogeneity of addictions and the neurobiological contributions to these disorders.

Indexed as

NeurosciencesAnimalsBehavior TherapyDrug TherapyHumansReinforcement, PsychologySubstance-Related Disorders

Identifiers

PMID21338880
PMCPMC3063555
OpenAlexW2019758887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.