ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2011
Comparison of CKD awareness in a screening population using the Modification of Diet in Renal Disease (MDRD) study and CKD Epidemiology Collaboration (CKD-EPI) equations.
Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 38 citations in OpenAlex.
- Awareness and Discussions About Chronic Kidney Disease Among African-Americans with Chronic Kidney Disease and Hypertension: a Mixed Methods Study.Journal of general internal medicine · 2020Trial
- Trends and Independent Correlates of Chronic Kidney Disease Awareness in US Adults: NHANES 1999-2020.American journal of nephrology · 2026Article
- Knowledge and Risk Perceptions of Chronic Kidney Disease Risk Factors among Women of Childbearing Age in Lagos State, Nigeria: From a Health Demography Approach.International journal of nephrology · 2022Article
- Disease Burden of Chronic Kidney Disease Due to Hypertension From 1990 to 2019: A Global Analysis.Frontiers in medicine · 2021Article
- Prevalence, risk-inducing lifestyle, and perceived susceptibility to kidney diseases by gender among Nigerians residents in South Western Nigeria.African health sciences · 2020Article
- Socioeconomic Determinants of Knowledge of Kidney Disease Among Residents in Nigerian Communities in Lagos State, Nigeria.Oman medical journal · 2019Article
- Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health.Oxidative medicine and cellular longevity · 2019Article
- The Landscape of Diabetic Kidney Disease in the United States.Current diabetes reports · 2018Review
- Awareness, self-management behaviors, health literacy and kidney function relationships in specialty practice.World journal of nephrology · 2018Article
- State-Level Awareness of Chronic Kidney Disease in the U.S.American journal of preventive medicine · 2017Article
- Health Literacy Not Associated with Chronic Kidney Disease Awareness.Health literacy research and practice · 2017Article
- Hospitalized patients frequently unaware of their chronic kidney disease.Journal of hospital medicine · 2015Article
- Prevalence of baseline chronic kidney disease in 2,769 Chinese patients with renal cancer: nephron-sparing treatment is still underutilized.World journal of urology · 2014Article
- The prevalence of chronic kidney disease in a primary care setting: a Swiss cross-sectional study.PloS one · 2013Article
- Treatment needs and diagnosis awareness in primary care patients with chronic kidney disease.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012Article
- Associations between access to care and awareness of CKD.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2012Article
- Physician utilization, risk-factor control, and CKD progression among participants in the Kidney Early Evaluation Program (KEEP).American journal of kidney diseases : the official journal of the National Kidney Foundation · 2012Article
- A Case for Early Screening for Diabetic Kidney Disease.Cardiorenal medicine · 2011Article
- Robot-assisted laparoscopic partial nephrectomy: Early single Canadian institution experience.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
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Authors and funding
7 authors at 6 institutions in 1 country.
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Abstract
backgroundLow awareness of chronic kidney disease (CKD) may reflect uncertainty about the accuracy or significance of a CKD diagnosis in individuals otherwise perceived to be low risk. Whether reclassification of CKD severity using the CKD Epidemiology Collaboration (CKD-EPI) equation to estimate glomerular filtration rate (GFR) modifies estimates of CKD awareness is unknown.
methodsIn this cross-sectional study, we used data collected from 2000-2009 for 26,213 participants in the Kidney Early Evaluation Program (KEEP), a community-based screening program, with CKD based on GFR estimated using the 4-variable Modification of Diet in Renal Disease (MDRD) Study equation and measurement of albuminuria. We assessed CKD awareness after CKD stage was reclassified using the CKD-EPI equation.
resultsOf 26,213 participants with CKD based on GFR estimated using the MRDR equation (eGFR(MDRD)), 23,572 (90%) also were classified with CKD based on eGFR(CKD-EPI). Based on eGFR(MDRD), 9.5% of participants overall were aware of CKD, as were 4.9%, 6.3%, 9.2%, 41.9%, and 59.2% with stages 1-5, respectively. Based on eGFR(CKD-EPI), 10.0% of participants overall were aware of CKD, as were 5.1%, 6.6%, 10.0%, 39.3%, and 59.4% with stages 1-5, respectively. Reclassification to a less advanced CKD stage using eGFR(CKD-EPI) was associated with lower odds for awareness (OR, 0.58; 95% CI, 0.50-0.67); reclassification to a more advanced stage was associated with higher odds for awareness (OR, 1.50; 95% CI, 1.05-2.13) after adjustment for confounding factors. Of participants unaware of CKD, 10.6% were reclassified as not having CKD using eGFR(CKD-EPI).
conclusionsUsing eGFR(CKD-EPI) led to a modest increase in overall awareness rates, primarily due to reclassification of low-risk unaware participants.
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