Evidence map›Paper›PMID 21338267›Full record

ReviewTissue engineering. Part B, Reviews2011

Adipose-derived stem cells in functional bone tissue engineering: lessons from bone mechanobiology.

Josephine C Bodle, Ariel D Hanson, Elizabeth G Loboa

Abstract readReview
In one paragraph

Review in Tissue engineering. Part B, Reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Role of PEMFs on Bone Healing: An In Vitro Study.International journal of molecular sciences · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Physical Stimulations for Bone and Cartilage Regeneration.Regenerative engineering and translational medicine · 2018
    Article
  9. Characterization andBiology open · 2018
    Article
  10. Article
  11. Article
  12. Primary cilia are sensors of electrical field stimulation to induce osteogenesis of human adipose-derived stem cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017
    Article
  13. Article
  14. Histological analysis ofTissue engineering and regenerative medicine · 2016
    Article
  15. Article
  16. Article
  17. Article
  18. Electrospun nanofiber scaffolds with gradations in fiber organization.Journal of visualized experiments : JoVE · 2015
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Josephine C BodleJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695-7115, USA.
Ariel D Hanson
Elizabeth G Loboa

Funding

Tensile Strain-Induced Osteogenesis of Human Mesenchymal Stem Cells in 3D CultureR03EB008790 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI LOBOA, ELIZABETH GRACE · 2010 to 2011
$142k
NIBIB NIH HHS R03EB008790PHS HHS 10KR51023
6 · The paper itself

Abstract

This review aims to highlight the current and significant work in the use of adipose-derived stem cells (ASC) in functional bone tissue engineering framed through the bone mechanobiology perspective. Over a century of work on the principles of bone mechanosensitivity is now being applied to our understanding of bone development. We are just beginning to harness that potential using stem cells in bone tissue engineering. ASC are the primary focus of this review due to their abundance and relative ease of accessibility for autologous procedures. This article outlines the current knowledge base in bone mechanobiology to investigate how the knowledge from this area has been applied to the various stem cell-based approaches to engineering bone tissue constructs. Specific emphasis is placed on the use of human ASC for this application.

Indexed as

Adipose TissueAnimalsHumansMechanotransduction, CellularOsteogenesisStem CellsStem Cell TransplantationTissue Engineering

Identifiers

PMID21338267
PMCPMC3098956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.