ArticleJournal of surgical oncology2011
Breast cancer in elderly women (≥ 80 years): variation in standard of care?
Article in Journal of surgical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Age-dependent differences in survival of patients with early breast cancer: analysis of SUCCESS A, B, C trials.Archives of gynecology and obstetrics · 2026Article
- De-Escalation of Treatment in Women Aged ≥80 Years with Breast Cancer: A Retrospective Analysis from Two Breast Centers.Current oncology (Toronto, Ont.) · 2025Article
- Invasive Breast Cancer Treatment Patterns in Women Age 80 and Over: A Report from the National Cancer Database.Clinical breast cancer · 2022Article
- Older breast cancer undertreatment: unconscious bias to undertreat-potential role for the international geriatric radiotherapy group?Translational cancer research · 2020Review
- The use of contralateral prophylactic mastectomy among elderly patients in the United States.Breast cancer research and treatment · 2019Article
- Treatment Strategies in Octogenarians with Early-Stage, High-Risk Breast Cancer.Annals of surgical oncology · 2018Article
- Breast diseases in women over the age of 65 in Monastir, Tunisia.The Pan African medical journal · 2018Article
- Management of Elderly Patients with Glioblastoma after CE.6.Frontiers in oncology · 2017Article
- Early-Stage Breast Cancer in the Octogenarian: Tumor Characteristics, Treatment Choices, and Clinical Outcomes.Annals of surgical oncology · 2016Article
- Locoregional and Distant Recurrence Patterns in Young versus Elderly Women Treated for Breast Cancer.International journal of breast cancer · 2015Article
- A prospective study of the use and effects of screening mammography in women aged 70 and older.Journal of the American Geriatrics Society · 2015Article
- Reliability of receptor assessment on core needle biopsy in breast cancer patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013Article
- Patient and physician decision styles and breast cancer chemotherapy use in older women: Cancer and Leukemia Group B protocol 369901.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012Article
- Pathological complete response in younger and older breast cancer patients.Archives of medical science : AMS · 2012Article
- Treatment Strategies in Elderly Patients With Operable, Hormone Receptor-negative Breast Cancer.Cancer diagnosis & prognosisArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe study aim was to investigate the methods of breast cancer diagnosis and treatment for women at advanced ages.
methodsWe identified 134 patients ≥ 80 years old treated for breast cancer. Data included patient and tumor characteristics, treatment, and outcomes.
resultsOf 134 women ≥ 80 years old, 146 breast cancers were diagnosed. Sixty-five (45%) were detected by mammography. Surgical therapy included partial mastectomy in 50% and mastectomy in 50%. Although 12 (9%) women had no axillary staging, 22 (16%) underwent axillary lymph node dissection for node-negative disease. Of 73 patients undergoing partial mastectomy, 34 (47%) received adjuvant radiation. Of 113 cancers with known estrogen receptor (ER) status, 83% were ER positive; 95% received endocrine therapy. Fourteen (10%) received adjuvant chemotherapy. Eleven (8%) were Her-2 neu-amplified; one patient received adjuvant trastuzumab. At follow-up, 87 (65%) patients were alive without evidence of disease, while 6 (4%) died of breast cancer.
conclusionsBreast cancer in women ≥ 80 years is more likely to be early-stage with favorable tumor biology. While most women eligible for anti-estrogen therapy received it, adjuvant radiation, chemotherapy, and/or trastuzumab were utilized infrequently. Despite these variations, older women with breast cancer are unlikely to suffer breast cancer-related mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.