ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2011
Dynamic analysis of BMP-responsive smad activity in live zebrafish embryos.
Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 55 citations in OpenAlex.
- Biochemical principles of SMAD signaling across the animal kingdom.The Biochemical journal · 2026Review
- Review
- Article
- Premature Vertebral Mineralization inCells · 2022Article
- The BMP Pathway in Blood Vessel and Lymphatic Vessel Biology.International journal of molecular sciences · 2021Review
- Utilizing Zebrafish Embryos to Reveal Disruptions in Dorsoventral Patterning.Current protocols · 2021Article
- Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification.Development (Cambridge, England) · 2021Article
- Tendon Cell Regeneration Is Mediated by Attachment Site-Resident Progenitors and BMP Signaling.Current biology : CB · 2020Article
- The mevalonate pathway is a crucial regulator of tendon cell specification.Development (Cambridge, England) · 2020Article
- BMP Signaling Gradient Scaling in the Zebrafish Pectoral Fin.Cell reports · 2020Article
- Zebrafish: A Resourceful Vertebrate Model to Investigate Skeletal Disorders.Frontiers in endocrinology · 2020Review
- The BMP ligand Pinhead together with Admp supports the robustness of embryonic patterning.Science advances · 2019Article
- The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension.Science signaling · 2019Article
- Somatic Mutations ofCells · 2019Article
- MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling.PLoS genetics · 2019Article
- Endodermal pouch-expressedBiology open · 2018Article
- BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks.BMC developmental biology · 2016Article
- Embryonic Ethanol Exposure Dysregulates BMP and Notch Signaling, Leading to Persistent Atrio-Ventricular Valve Defects in Zebrafish.PloS one · 2016Article
- Article
- Sensory hair cell regeneration in the zebrafish lateral line.Developmental dynamics : an official publication of the American Association of Anatomists · 2014Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Bone morphogenetic proteins (BMPs) are critical players in development and disease, regulating such diverse processes as dorsoventral patterning, palate formation, and ossification. These ligands are classically considered to signal via BMP receptor-specific Smad proteins 1, 5, and 8. To determine the spatiotemporal pattern of Smad1/5/8 activity and thus canonical BMP signaling in the developing zebrafish embryo, we generated a transgenic line expressing EGFP under the control of a BMP-responsive element. EGFP is expressed in many established BMP signaling domains and is responsive to alterations in BMP type I receptor activity and smad1 and smad5 expression. This transgenic Smad1/5/8 reporter line will be useful for determining ligand and receptor requirements for specific domains of BMP activity, as well as for genetic and pharmacological screens aimed at identifying enhancers or suppressors of canonical BMP signaling.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.