ArticleMagnetic resonance in medicine2011
Liver stiffness assessment by tagged MRI of cardiac-induced liver motion.
Article in Magnetic resonance in medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- In vivo elastography of the human retina using light-evoked intrinsic actuation.bioRxiv : the preprint server for biology · 2026Article
- Harnessing intrinsic cardiac motion vs. external mechanical vibrations: a comparison of MRI cine-tagging and MR elastography for liver fibrosis assessment.The British journal of radiology · 2025Article
- Native-resolution myocardial principal Eulerian strain mapping using convolutional neural networks and Tagged Magnetic Resonance Imaging.Computers in biology and medicine · 2022Article
- Cardiac-induced liver deformation as a measure of liver stiffness using dynamic imaging without magnetization tagging-preclinical proof-of-concept, clinical translation, reproducibility and feasibility in patients with cirrhosis.Abdominal radiology (New York) · 2021Article
- MR elastography of liver at 3 Tesla: comparison of gradient-recalled echo (GRE) and spin-echo (SE) echo-planar imaging (EPI) sequences and agreement across stiffness measurements.Abdominal radiology (New York) · 2019Article
- 3-D Measurements of Acceleration-Induced Brain Deformation via Harmonic Phase Analysis and Finite-Element Models.IEEE transactions on bio-medical engineering · 2019Article
- Prognostic Role of Liver Stiffness Measurements Using Magnetic Resonance Elastography in Patients with Compensated Chronic Liver Disease.European radiology · 2018Article
- Ultrasound or MR elastography of liver: which one shall I use?Abdominal radiology (New York) · 2018Review
- Liver Stiffness Measured by Two-Dimensional Shear-Wave Elastography: Prognostic Value after Radiofrequency Ablation for Hepatocellular Carcinoma.Liver cancer · 2018Article
- Hepatic stiffness measurement by using MR elastography: prognostic values after hepatic resection for hepatocellular carcinoma.European radiology · 2017Article
- MR elastography of the liver at 3.0 T in diagnosing liver fibrosis grades; preliminary clinical experience.European radiology · 2016Article
- Magnetization-tagged MRI is a simple method for predicting liver fibrosis.Clinical and molecular hepatology · 2016Article
- Assessment of liver fibrosis using fast strain-encoded MRI driven by inherent cardiac motion.Magnetic resonance in medicine · 2015Article
- Non-invasive detection of liver fibrosis: MR imaging features vs. MR elastography.Abdominal imaging · 2015Article
- Liver stiffness assessment with tagged MRI of cardiac-induced liver motion in cirrhosis patients.Journal of magnetic resonance imaging : JMRI · 2014Article
- Optimization of tagged MRI for quantification of liver stiffness using computer simulated data.PloS one · 2014Article
- Diffusion-weighted imaging of the liver: usefulness of ADC values in the differential diagnosis of focal lesions and effect of ROI methods on ADC measurements.Magma (New York, N.Y.) · 2013Article
- Molecular MRI of liver fibrosis by a peptide-targeted contrast agent in an experimental mouse model.Investigative radiology · 2013Article
- Review of MR elastography applications and recent developments.Journal of magnetic resonance imaging : JMRI · 2012Review
- Noncontrast functional MRI of the kidneys.Current urology reports · 2012Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Cirrhosis is an important and growing public health problem, affecting millions of Americans and many more people internationally. A pathological hallmark of the progression to cirrhosis is the development of liver fibrosis, so that monitoring the appearance and progression of liver fibrosis can be used to guide therapy. Here, we report a method to use magnetization-tagged magnetic resonance imaging to measure the cardiac-induced motion and deformation in the liver, as a means for noninvasively assessing liver stiffness, which is related to fibrosis. The initial results show statistically significant differences between healthy and cirrhotic subjects in the direct comparisons of the maximum displacement (mm), and the maximum (P1) and minimum (P2) two-dimensional strains, through the cardiac cycle (3.514 ± 0.793, 2.184 ± 0.611; 0.116 ± 0.043, 0.048 ± 0.011; -0.094 ± 0.020, -0.041 ± 0.015; healthy, cirrhosis, respectively; P < 0.005 for all). There are also significant differences in the displacement-normalized P1 and P2 strains (mm(-1) ) (0.030 ± 0.008, 0.017 ± 0.007; -0.024 ± 0.006, -0.013 ± 0.004; healthy, cirrhosis, respectively; P < 0.005 for all). Therefore, this noninvasive imaging-based method is a promising means to assess liver stiffness using clinically available imaging tools.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.