ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2011
Impact of radiotherapy on pain relief and recalcification in plasma cell neoplasms: long-term experience.
Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- [Benefits of radiotherapy for patients with solitary plasmacytoma or multiple myeloma].Der Radiologe · 2022Pooled it
- Single vs. multiple fraction regimens for palliative radiotherapy treatment of multiple myeloma : A prospective randomised study.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2017Trial
- Effects of Radiotherapy in the treatment of multiple myeloma: a retrospective analysis of a Single Institution.Radiation oncology (London, England) · 2015Trial
- Clinical factors associated with jawbone remineralization after nonsurgical treatment and imaging-based insights into its processes.Oral radiology · 2026Article
- The Role of Radiotherapy for Patients With Multiple Myeloma in the Modern Era: A Real World Single-Centre Experience.EJHaem · 2025Article
- Excellent long-term pain response and local control following postoperative radiotherapy in patients with multiple myeloma.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Article
- Article
- How Can Imaging Help the Radiation Oncologist in Multiple Myeloma Treatment.Medicina (Kaunas, Lithuania) · 2020Review
- Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2017Article
- Reconstruction of multiple myeloma lesions around the pelvis and acetabulum.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2015Review
- [Radiotherapy for solitary plasmacytoma and multiple myeloma].Der Radiologe · 2014Article
- Review
- International Myeloma Working Group recommendations for the treatment of multiple myeloma-related bone disease.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2013Article
- Diagnosis and treatment of bone disease in multiple myeloma: spotlight on spinal involvement.Scientifica · 2013Review
- Prevention and treatment of myeloma bone disease.Current hematologic malignancy reports · 2012Review
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the impact of radiotherapy on pain relief and on recalcification in patients with osteolytic lesions due to plasma cell neoplasm. PATIENTS AND
methodsPain relief was evaluated according to a 0-10 verbal numerical rating scale (NRS) and recalcification was measured using radiological imaging.
resultsFrom 1996-2007, 52 patients were treated (Table 1). Median total dose was 38 Gy (range, 16-50 Gy). Pain be-fore radiotherapy was reported by 45 of 52 (86.5%) patients (Table 2) as being severe (8 ≤ NRS ≤ 10) in 5 (11%), moderate (5 ≤ NRS ≤ 7) in 27 (60%), and mild in 13 (29%). Pain relief was achieved in 41 of 45 patients (91%): complete relief was obtained in 21 (51.2%) and partial relief in 20 patients (48.8%); patients with severe pain experienced resolution and none present-ed an increase of pain. Drugs reduction/suspension was achieved in 7 of the 21 patients with complete response. Of 42 patients evaluable for recalcification (Table 3), 21 (50%) presented a radiological response, which was identified as complete in 16 (38%).
conclusionOur data confirm the effectiveness of radiotherapy for pain relief, including a reduction in drug intake, and on recalcification, thus, supporting its use in a multidisciplinary approach.
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