ArticlePlant physiology2011
The Soybean Rhg1 locus for resistance to the soybean cyst nematode Heterodera glycines regulates the expression of a large number of stress- and defense-related genes in degenerating feeding cells.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 137 citations in OpenAlex.
- AATRhg1 is a tonoplast protein that alters amino acid, metabolic, and defense responses and nematode resistance.Plant physiology · 2026Article
- Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- GmSNAP14: a key contributor to soybean cyst nematode resistance in soybean.The New phytologist · 2026Article
- Haplotype-phased 'Ottawa 3' genome unravels differential reaction of apple rootstock roots to mixed viral infection.The Plant journal : for cell and molecular biology · 2026Article
- Evolution and Functional Dynamics of the BAG Gene Family in Passion Fruit (Plants (Basel, Switzerland) · 2025Article
- The AP2/ERF transcription factor GmTINY mediates ethylene regulation of Rhg1-conferred resistance against soybean cyst nematode.Plant communications · 2025Article
- A novel toolbox of GATEWAY-compatible vectors for rapid functional gene analysis in soybean composite plants.Plant cell reports · 2025Article
- Discovery of two tightly linked soybean genes at the qSCN10 (O) locus conferring broad-spectrum resistance to soybean cyst nematode.Communications biology · 2025Article
- Protein Dynamics in Plant Immunity: Insights into Plant-Pest Interactions.International journal of molecular sciences · 2024Review
- The molecular dynamics between reactive oxygen species (ROS), reactive nitrogen species (RNS) and phytohormones in plant's response to biotic stress.Plant cell reports · 2024Review
- Impact of Rhg1 copy number variation on a soybean cyst nematode resistance transcriptional network.G3 (Bethesda, Md.) · 2024Article
- GmSABP2-1 encodes methyl salicylate esterase and functions in soybean defense against soybean cyst nematode.Plant cell reports · 2024Article
- Syncytium Induced by Plant-Parasitic Nematodes.Results and problems in cell differentiation · 2024Review
- Loss-of-function of an α-SNAP gene confers resistance to soybean cyst nematode.Nature communications · 2023Article
- Research progress on the functional study of host resistance-related genes against Heterodera glycines.Crop health · 2023Review
- Identification of genes governing resistance to PCN (Globodera rostochiensis) through transcriptome analysis in Solanum tuberosum.Functional & integrative genomics · 2023Article
- Single Nematode Transcriptomic Analysis, Using Long-Read Technology, Reveals Two Novel Virulence Gene Candidates in the Soybean Cyst Nematode,International journal of molecular sciences · 2023Article
- Soybean transporter AAT Rhg1 abundance increases along the nematode migration path and impacts vesiculation and ROS.Plant physiology · 2023Article
- Identification of QTL, QTL-by-environment interactions, and their candidate genes for resistance HG Type 0 and HG Type 1.2.3.5.7 in soybean using 3VmrMLM.Frontiers in plant science · 2023Article
- Functional insights of plant bcl-2-associated ahanogene (BAG) proteins: Multi-taskers in diverse cellular signal transduction pathways.Frontiers in plant science · 2023Review
9 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To gain new insights into the mechanism of soybean (Glycine max) resistance to the soybean cyst nematode (Heterodera glycines), we compared gene expression profiles of developing syncytia in soybean near-isogenic lines differing at Rhg1 (for resistance to Heterodera glycines), a major quantitative trait locus for resistance, by coupling laser capture microdissection with microarray analysis. Gene expression profiling revealed that 1,447 genes were differentially expressed between the two lines. Of these, 241 (16.8%) were stress- and defense-related genes. Several stress-related genes were up-regulated in the resistant line, including those encoding homologs of enzymes that lead to increased levels of reactive oxygen species and proteins associated with the unfolded protein response. These results indicate that syncytia induced in the resistant line are undergoing severe oxidative stress and imbalanced endoplasmic reticulum homeostasis, both of which likely contribute to the resistance reaction. Defense-related genes up-regulated within syncytia of the resistant line included those predominantly involved in apoptotic cell death, the plant hypersensitive response, and salicylic acid-mediated defense signaling; many of these genes were either partially suppressed or not induced to the same level by a virulent soybean cyst nematode population for successful nematode reproduction and development on the resistant line. Our study demonstrates that a network of molecular events take place during Rhg1-mediated resistance, leading to a highly complex defense response against a root pathogen.
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