ArticleNeuroImage2011
FADTTS: functional analysis of diffusion tensor tract statistics.
Article in NeuroImage, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed.
- Erratum: "Tract-specific white matter microstructure associated with early cognitive development in infants" [Neuroimage Rep 6 (2026) 100336].Neuroimage. Reports · 2026Article
- Computation and resource efficient genome-wide association analysis for large-scale imaging studies.Nature communications · 2026Article
- Long-term associations between perinatal factors and white matter microstructure at 8-10 years.Frontiers in human neuroscience · 2026Article
- Computation and resource efficient genome-wide association analysis for large-scale imaging studies.medRxiv : the preprint server for health sciences · 2025Article
- Article
- White matter microstructure and functional connectivity in the brains of infants with Turner syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Subtle microstructural alterations in white matter tracts involved in socio-emotional processing after very preterm birth.NeuroImage. Clinical · 2024Article
- Estimation for the bivariate quantile varying coefficient model with application to diffusion tensor imaging data analysis.Biostatistics (Oxford, England) · 2023Article
- The Brain and Early Experience Study: Protocol for a Prospective Observational Study.JMIR research protocols · 2022Article
- DADP: Dynamic abnormality detection and progression for longitudinal knee magnetic resonance images from the Osteoarthritis Initiative.Medical image analysis · 2022Article
- High-Dimensional Spatial Quantile Function-on-Scalar Regression.Journal of the American Statistical Association · 2022Article
- Genome-Wide Association Analysis of Neonatal White Matter Microstructure.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Infantile Iron Deficiency Affects Brain Development in Monkeys Even After Treatment of Anemia.Frontiers in human neuroscience · 2021Article
- (TS)NeuroImage · 2020Article
- Trajectories from Distribution-valued Functional Curves: A Unified Wasserstein FrameworkMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2020Article
- Automatic, Age Consistent Reconstruction of the Corpus Callosum Guided by Coherency From In Utero Diffusion-Weighted MRI.IEEE transactions on medical imaging · 2020Article
- The joint effect of aging and HIV infection on microstructure of white matter bundles.Human brain mapping · 2019Article
- Tensor decomposition of hyperspectral images to study autofluorescence in age-related macular degeneration.Medical image analysis · 2019Article
- FSEM: Functional Structural Equation Models for Twin Functional Data.Journal of the American Statistical Association · 2019Article
- Impact of white matter hyperintensities on surrounding white matter tracts.Neuroradiology · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The aim of this paper is to present a functional analysis of a diffusion tensor tract statistics (FADTTS) pipeline for delineating the association between multiple diffusion properties along major white matter fiber bundles with a set of covariates of interest, such as age, diagnostic status and gender, and the structure of the variability of these white matter tract properties in various diffusion tensor imaging studies. The FADTTS integrates five statistical tools: (i) a multivariate varying coefficient model for allowing the varying coefficient functions in terms of arc length to characterize the varying associations between fiber bundle diffusion properties and a set of covariates, (ii) a weighted least squares estimation of the varying coefficient functions, (iii) a functional principal component analysis to delineate the structure of the variability in fiber bundle diffusion properties, (iv) a global test statistic to test hypotheses of interest, and (v) a simultaneous confidence band to quantify the uncertainty in the estimated coefficient functions. Simulated data are used to evaluate the finite sample performance of FADTTS. We apply FADTTS to investigate the development of white matter diffusivities along the splenium of the corpus callosum tract and the right internal capsule tract in a clinical study of neurodevelopment. FADTTS can be used to facilitate the understanding of normal brain development, the neural bases of neuropsychiatric disorders, and the joint effects of environmental and genetic factors on white matter fiber bundles. The advantages of FADTTS compared with the other existing approaches are that they are capable of modeling the structured inter-subject variability, testing the joint effects, and constructing their simultaneous confidence bands. However, FADTTS is not crucial for estimation and reduces to the functional analysis method for the single measure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.