Evidence map›Paper›PMID 21334166›Full record

ArticleJournal of vascular surgery2011

A regional quality improvement effort to increase beta blocker administration before vascular surgery.

Philip P Goodney, Jens Eldrup-Jorgensen, Brian W Nolan, Daniel J Bertges, Donald S Likosky, Jack L Cronenwett, Vascular Study Group of New England

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of vascular surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Preoperative optimization of the vascular surgery patient.Vascular health and risk management · 2015
    Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Philip P GoodneyDartmouth-Hitchcock Medical Center, Lebanon, NH, USA. philip.goodney@hitchcock.org
Jens Eldrup-Jorgensen
Brian W Nolan
Daniel J Bertges
Donald S Likosky
Jack L Cronenwett
Vascular Study Group of New England
Dartmouth Institute for Health Policy and Clinical Practice · USUniversity of Vermont · US

Funding

Understanding Variation in Treatment Intensity with Lower Extremity PADK08HL105676 · NHLBI · DARTMOUTH COLLEGE · PI GOODNEY, PHILIP P · 2010 to 2014
$700k
NHLBI NIH HHS K08 HL105676NIMHD NIH HHS L32 MD006323
6 · The paper itself

Abstract

objectiveTo determine if a regional quality improvement effort can increase beta-blocker utilization prior to vascular surgery and decrease the incidence of postoperative myocardial infarction (POMI).

methodsA quality improvement effort to increase perioperative beta blocker utilization was implemented in 2003 at centers participating in the Vascular Study Group of New England (VSGNE). A 90% target was set and feedback given at biannual meetings. Beta blocker utilization (<1 month preoperative versus chronic) and POMI rates were prospectively collected for patients undergoing open abdominal aortic aneurysm (AAA) repair (n = 926) and lower extremity bypass (LEB; n = 2,123) from 2003 through 2008. Predictors of POMI were determined using multivariate logistic regression. Rates of beta blocker administration and POMI were analyzed over time, and across strata of patient risk based on a multivariate model.

resultsPerioperative beta blocker treatment increased from 68% of patients in the first 3 months of 2005 to 88% by the last 3 months of 2008 (P < .001). In 2003, 44% of patients not on chronic beta blockers were treated with preoperative beta blockers; by 2008, 78% of patients not on chronic beta blockers were started perioperatively on these medications (P < .001). Beta blocker utilization increased across all centers and surgeons participating during the study period, and increased in patients of low, medium, and high cardiac risk. However, the rate of POMI did not change over time (5.2% in 2003, 5.5% in 2008; P = .876), although a trend towards lower POMI rate was seen in patients on preoperative beta blockers (4.4% in 2003-2005, 2.6% in 2006-2008; P = .43). In multivariable modeling we found that age >70 (odds ratio [OR], 2.1), positive stress test (OR, 2.2), congestive heart failure (CHF; OR, 1.7), chronic beta blocker administration (OR, 1.7), resting heart rate <70 (OR, 1.8), and diabetes (OR, 1.6) were associated with POMI. Resting heart rate was similar for patients on chronic (67), preoperative (70), and no beta blockers (70; P = .521).

conclusionsOur regional quality improvement effort successfully increased perioperative beta blocker utilization. However, this was not associated with reduced rates of POMI or resting heart rate. While this demonstrates the effectiveness of regional quality improvement efforts in changing practice patterns, further work is necessary to more precisely identify those patients who will benefit from beta blockade at the time of vascular surgery.

Indexed as

Hospital PlanningOutcome and Process Assessment, Health CareQuality ImprovementAdrenergic beta-AntagonistsAdultAgedAged, 80 and overChi-Square DistributionDrug Administration ScheduleDrug UtilizationDrug Utilization ReviewEvidence-Based MedicineFemaleGuideline AdherenceHeart RateHumansAdrenergic beta-Antagonists

Identifiers

PMID21334166
PMCPMC3096676
OpenAlexW2030101334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.