ReviewSeminars in cell & developmental biology2011
The emerging role of RNA in the regulation of gene transcription in human cells.
Review in Seminars in cell & developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Melatonin: Regulation of Biomolecular Condensates in Neurodegenerative Disorders.Antioxidants (Basel, Switzerland) · 2021Review
- Interspecies RNA Interactome of Pathogen and Host in a Heritable Defensive Strategy.Frontiers in microbiology · 2021Article
- Long Non-Coding RNA Modulation of VEGF-A during Hypoxia.Non-coding RNA · 2018Article
- Article
- Promoter-Associated RNAs Regulate HSPC152 Gene Expression in Malignant Melanoma.Non-coding RNA · 2016Article
- A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies.Nucleic acids research · 2014Article
- An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription.Molecular therapy : the journal of the American Society of Gene Therapy · 2014Article
- RNAs nonspecifically inhibit RNA polymerase II by preventing binding to the DNA template.RNA (New York, N.Y.) · 2014Article
- Evolutionary conservation of long non-coding RNAs; sequence, structure, function.Biochimica et biophysica acta · 2014Review
- Peripheral blood mononuclear cells as a laboratory to study dementia in the elderly.BioMed research international · 2014Review
- An Algorithm for Generating Small RNAs Capable of Epigenetically Modulating Transcriptional Gene Silencing and Activation in Human Cells.Molecular therapy. Nucleic acids · 2013Article
- Chromatin, non-coding RNAs, and the expression of HIV.Viruses · 2013Review
- CHH islands: de novo DNA methylation in near-gene chromatin regulation in maize.Genome research · 2013Article
- Long non-coding RNA targeting and transcriptional de-repression.Nucleic acid therapeutics · 2013Review
- Article
- Snapshots: chromatin control of viral infection.Virology · 2013Review
- Cis-acting noncoding RNAs: friends and foes.Nature structural & molecular biology · 2012Review
- Cellular and molecular basis of intestinal barrier dysfunction in the irritable bowel syndrome.Gut and liver · 2012Article
- Article
- Transcriptional silencing by hairpin RNAs complementary to a gene promoter.Nucleic acid therapeutics · 2012Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Recent evidence suggests that particular species of non-coding RNAs can modulate gene transcription in human cells. While such observations were in the past relegated to imprinted genes, it is now becoming apparent that several different genes in differentiated cells may be under some form of RNA based regulatory control. Studies carried out to date have begun to discern the mechanism of action whereby non-coding RNAs modulate gene transcription by the targeted recruitment of epigenetic silencing complexes to homology containing loci in the genome. The results of these studies will be considered in detail as well as the implications that a vast array of non-coding RNA based regulatory networks may be operative in human cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.