ArticleBMC public health2011
The relationship of air pollution and surrogate markers of endothelial dysfunction in a population-based sample of children.
Article in BMC public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 48 citations in OpenAlex.
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- Alveolar Type II Cell Damage and Nrf2-SOD1 Pathway Downregulation Are Involved in PMInternational journal of environmental research and public health · 2022Article
- DNA methylation: a potential mediator between air pollution and metabolic syndrome.Clinical epigenetics · 2022Review
- Immune biomarkers link air pollution exposure to blood pressure in adolescents.Environmental health : a global access science source · 2020Article
- Air pollution and hospitalization: an autoregressive distributed lag (ARDL) approach.Environmental science and pollution research international · 2020Article
- Adolescent Haze-Related Knowledge Level Study: A Cross-Sectional Survey With Sensitivity Analysis.Frontiers in public health · 2020Article
- Air pollution and hospitalizations in the largest Brazilian metropolis.Revista de saude publica · 2017Article
- First report on the association of drinking water hardness and endothelial function in children and adolescents.Archives of medical science : AMS · 2014Article
- A synergistic vascular effect of airborne particulate matter and nickel in a mouse model.Toxicological sciences : an official journal of the Society of Toxicology · 2013Article
- NHLBI integrated pediatric guidelines: battle for a future free of cardiovascular disease.Future cardiology · 2013Article
- Environmental air pollution and acute cerebrovascular complications: an ecologic study in tehran, iran.International journal of preventive medicine · 2012Article
- Synergistic effects of genetic polymorphism and air pollution on markers of endothelial dysfunction in children.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012Article
- Association of particulate air pollution and secondhand smoke on endothelium-dependent brachial artery dilation in healthy children.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2012Article
- Obesity and air pollution: global risk factors for pediatric non-alcoholic fatty liver disease.Hepatitis monthly · 2011Article
- Overweight, air and noise pollution: Universal risk factors for pediatric pre-hypertension.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2011Article
- Genetic variation in the association of air pollutants with a biomarker of vascular injury in children and adolescents in Isfahan, Iran.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2011Article
- What health professionals should know about the health effects of air pollution and climate change on children and pregnant mothers.Iranian journal of nursing and midwifery research · 2011Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to assess the relationship of air pollution and plasma surrogate markers of endothelial dysfunction in the pediatric age group.
methodsThis cross-sectional study was conducted in 2009-2010 among 125 participants aged 10-18 years. They were randomly selected from different areas of Isfahan city, the second large and air-polluted city in Iran. The association of air pollutants' levels with serum thrombomodulin (TM) and tissue factor (TF) was determined after adjustment for age, gender, anthropometric measures, dietary and physical activity habits.
resultsData of 118 participants was complete and was analyzed. The mean age was 12.79 (2.35) years. The mean pollution standards index (PSI) value was at moderate level, the mean particular matter measuring up to 10 μm (PM10) was more than twice the normal level. Multiple linear regression analysis showed that TF had significant relationship with all air pollutants except than carbon monoxide, and TM had significant inverse relationship with ozone. The odds ratio of elevated TF was significantly higher in the upper vs. the lowest quartiles of PM10, ozone and PSI. The corresponding figures were in opposite direction for TM.
conclusionsThe relationship of air pollutants with endothelial dysfunction and pro-coagulant state can be an important factor in the development of atherosclerosis from early life. This finding should be confirmed in future longitudinal studies. Concerns about the harmful effects of air pollution on children's health should be considered a top priority for public health policy; it should be underscored in primordial and primary prevention of chronic diseases.
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