ArticleTransfusion2011
Symptomatic parvovirus B19 infection caused by blood component transfusion.
Article in Transfusion, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Overall prevalence of human parvovirus B19 among blood donors in mainland China: A PRISMA-compliant meta-analysis.Medicine · 2020Pooled it
- Insights into parvovirus B19 clinical and virological dynamics among blood donors.Le infezioni in medicina · 2026Article
- Detection and analysis of parvovirus B19 among blood donors in a regional blood center in Eastern China.Heliyon · 2024Article
- Review
- New atypical epidemiological profile of parvovirus B19 revealed by molecular screening of blood donations, France, winter 2023/24.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024Article
- Wild Felids Blood Group System.Animals : an open access journal from MDPI · 2021Review
- Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar.Viruses · 2021Article
- Viral metagenomics in blood donations with post-donation illness reports from Brazil.Blood transfusion = Trasfusione del sangue · 2021Article
- Enhanced Cell-Based Detection of Parvovirus B19V Infectious Units According to Cell Cycle Status.Viruses · 2020Article
- The human parvovirus B19/human immunodeficiency virus co-infection in healthy eligible voluntary blood donors at the Blood Transfusion National Center in Kinshasa.The Pan African medical journal · 2020Article
- Seroprevalence of antibodies to primate erythroparvovirus 1 (B19V) in Australia.BMC infectious diseases · 2018Article
- Pathogens transmitted in red blood cell transfusions: An up-to-date table.Proceedings (Baylor University. Medical Center) · 2018Review
- Parvovirus B19: What Is the Relevance in Transfusion Medicine?Frontiers in medicine · 2018Review
- Parvovirus B19 in the Context of Hematopoietic Stem Cell Transplantation: Evaluating Cell Donors and Recipients.Transplantation direct · 2017Article
- Human parvovirus B19 in patients with beta thalassemia major from Tehran, Iran.Blood research · 2017Article
- Human Parvoviruses.Clinical microbiology reviews · 2017Review
- Parvovirus B19 Passive Transmission by Transfusion of Intercept® Blood System-Treated Platelet Concentrate.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2016Article
- Human Parvovirus B19 and blood product safety: a tale of twenty years of improvements.Blood transfusion = Trasfusione del sangue · 2015Review
- Parvovirus b19 infections and blood counts in blood donors.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2014Article
- Transfusion-transmitted emerging infectious diseases: 30 years of challenges and progress.Transfusion · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough a risk of transfusion-transmitted human parvovirus B19V (TT-B19V) infection has been a concern, there have been very few reports of clinically relevant TT-B19V caused by the transfusion of a B19V-containing blood component. It has therefore been a matter of debate whether a universal B19V screening with an appropriate sensitivity is required. STUDY DESIGN AND
methodsThrough the Japanese Red Cross hemovigilance system, clinical reports on possible TT-B19V were collected from 1999 to 2008, during which B19V donor screening (sensitivity, 10(10) IU/mL) was conducted and repository blood samples from donors were available.
resultsEight patients with TT-B19V caused by component transfusion have been identified. Four patients developed sustained anemia and pure red blood cell (RBC) aplasia and one patient developed pancytopenia. The underlying diseases in these five patients were either hematologic malignancy or hemolytic diseases. The viral loads of the responsible components for these cases ranged from 10(3) to 10(8) IU/mL. Two patients who underwent surgical treatment without any hematologic disorder exhibited only moderate symptoms. The B19V DNA sequence identity between a patient and the linked blood donor was confirmed in five of the eight patients. All of the components responsible for the eight cases were positive for anti-B19V immunoglobulin (Ig)M.
conclusionVulnerability to serious B19V-related hematologic disorders depended on the patient's underlying disease state of an enhanced erythropoiesis, not on the viral load of the component transfused. To prevent clinically relevant TT-B19V, a strategy is suggested in which patients at risk of acquiring RBC aplasia or pancytopenia are targeted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.