Evidence map›Paper›PMID 21332297›Full record

Trial reportNordic journal of psychiatry2011

Effects of high aerobic intensity training in patients with schizophrenia: a controlled trial.

Jørn Heggelund, Geir E Nilsberg, Jan Hoff, Gunnar Morken, Jan Helgerud

Registry-linked trialOpen access · bronzeAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nordic journal of psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00286299 (Physiological and Psychiatric Effects From Aerobic High Intensity Endurance Training and Maximal Strength Training in Patients Suffering From Schizophrenia), which is not on this map. Cited by 52 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 13 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00286299 nacompletednot on this map

Physiological and Psychiatric Effects From Aerobic High Intensity Endurance Training and Maximal Strength Training in Patients Suffering From Schizophrenia: A Controlled Clinical Trial.

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2005 to 2008Enrolled33ConditionsSchizophrenia, Cardiovascular DiseaseArmsAerobic high-intensity interval training (AIT), Computer game training (CG), Maximal strength training
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 13 syntheses or guidelines pooled it, 129 citations in OpenAlex.

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  5. Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023
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  7. Video games for people with schizophrenia.The Cochrane database of systematic reviews · 2021
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  10. Short-Term (<8 wk) High-Intensity Interval Training in Diseased Cohorts.Medicine and science in sports and exercise · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jørn HeggelundDepartment of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway. Jorn.Heggelund@ntnu.no
Geir E Nilsberg
Jan Hoff
Gunnar Morken
Jan Helgerud
Norwegian University of Science and Technology · NOSt Olav's University Hospital · NOTelemark Research Institute · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with schizophrenia have a high risk of cardiovascular disease (CVD). High aerobic intensity training (HIT) improve peak oxygen uptake (VO(2peak)), net mechanical efficiency of walking and risk factors for CVD but has not been investigated in patients with schizophrenia.

aimsTo investigate effects from HIT on VO(2peak), net mechanical efficiency of walking and risk factors for CVD in patients with schizophrenia.

methods25 inpatients (F20-29, ICD-10) were allocated to either HIT or playing computer games (CG), 3 days per week for 8 weeks. HIT consisted of 4 × 4-min intervals with 3-min break periods, at 85-95% and 70% of peak heart rate, respectively.

results12 and seven patients completed HIT and CG, respectively. The baseline VO(2peak) in both groups combined (n = 19) was 36.8 ± 8.2 ml/kg/min and 3.12 ± 0.55 l/min. The HIT group improved VO(2peak) by 12% from 3.17 ± 0.59 to 3.56 ± 0.68 l/min (P < 0.001), more than the CG group (P = 0.014). Net mechanical efficiency of walking improved by 12% in the HIT group from 19.8 ± 3.0% to 22.2 ± 4.5% (P = 0.005), more than the CG group (P = 0.031). The psychiatric symptoms, expressed as the Positive and Negative Syndrome Scale (PANSS) and the Calgary Depression Scale for Schizophrenia (CDSS), did not improve in either group.

conclusionsVO(2peak) and net mechanical efficiency of walking improved significantly by 8 weeks of HIT. HIT should be included in rehabilitation in order to improve physical capacity and contribute risk reduction of CVD.

Indexed as

Exercise TherapyAdultCardiovascular DiseasesFemaleHeart RateHumansMaleOxygen ConsumptionPhysical FitnessRiskSchizophreniaVideo GamesWalkingYoung Adult

Identifiers

PMID21332297
PMCPMC3169036
OpenAlexW2004675059

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.