Evidence map›Paper›PMID 21331686›Full record

ArticleJapanese journal of ophthalmology2011

Clinical features of adenoviral conjunctivitis at the early stage of infection.

Koki Aoki, Hisatoshi Kaneko, Nobuyoshi Kitaichi, Takeshi Ohguchi, Yoshitsugu Tagawa, Shigeaki Ohno

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Japanese journal of ophthalmology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  4. Viral Conjunctivitis.Viruses · 2023
    Review
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  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Koki AokiDepartment of Ophthalmology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Hisatoshi Kaneko
Nobuyoshi Kitaichi
Takeshi Ohguchi
Yoshitsugu Tagawa
Shigeaki Ohno
Hokkaido University · JPFukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBecause adenoviral conjunctivitis is a contagious disease, prompt and accurate diagnosis in the early stage of infection is necessary to prevent epidemics. We evaluated and compared the clinical features of adenoviral conjunctivitis at the first medical examination with those of nonadenoviral follicular conjunctivitis.

methodsThe clinical features of 102 patients with suspected adenoviral conjunctivitis at the first medical examination were retrospectively reviewed. Human adenovirus (HAdV) DNA in samples from the patients was detected by polymerase chain reaction, and HAdV DNA-positive and HAdV DNA-negative patients were respectively assigned to adenoviral and nonadenoviral follicular conjunctivitis groups. The two groups were compared for bilaterality, intrafamilial infection, multiple subepithelial corneal infiltrates (MSI), preauricular lymphadenopathy, and severity of conjunctivitis.

resultsAdenoviral conjunctivitis and nonadenoviral conjunctivitis were diagnosed in 68 and 34 patients, respectively. Bilaterality, intrafamilial infection, and MSI showed significant intergroup differences. Remarkably, MSI was observed in 42.6% of the patients in the early stage of infection. There were no significant intergroup differences in preauricular lymphadenopathy or severity of conjunctivitis at any stage.

conclusionsTo accurately diagnose adenoviral conjunctivitis in the early stage, bilateral conjunctival conditions, history of intrafamilial infection, and MSI should be checked, even in cases of mild or moderate follicular conjunctivitis.

Indexed as

AdenoviridaeAdenovirus Infections, HumanAdultAntigens, ViralConjunctivaConjunctivitis, ViralDNA, ViralFemaleHumansMalePolymerase Chain ReactionRetrospective StudiesAntigens, ViralDNA, Viral

Identifiers

PMID21331686
OpenAlexW2138476955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.