Evidence map›Paper›PMID 21331642›Full record

ArticleDer Internist2011

[Optimal lipid treatment: possibilities and current limitations].

G Klose

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Der Internist, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

G KloseInternistische Praxisgemeinschaft Dres. T. Beckenbauer, S. Maierhof, Hans-Thoma-Strasse 31, Bremen, Germany. klose.bremen@t-online.de
Praxis · EE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prevention is a major contributor to the decline in cardiovascular morbidity and mortality. Cardiovascular diseases still are the leading cause of death (42%) in Germany and indicate unmet preventive needs. Limitations of healthy lifestyle, the basis of many recommendations, include insufficient compliance and efficacy in individual cases. In their latest metaanalysis the Cholesterol Treatment Trialists' Collaborators showed updated estimates of treatment effects of statins including more or less intensive regimens.The average reduction in major vascular events was 21% per 1.0 mmol/l reduction in LDL cholesterol. Appropriateness of receiving lipid modulating treatment in the population will be discussed in the light of controversial recommendations in treatment strategies. Residual risk in statin treated patients may be ameliorated by options beyond LDL-lowering. Suggestions for clinical practice are provided on the background of clinical relevant characteristics of current lipid lowering drugs and future developments are outlined.

Indexed as

Anion Exchange ResinsAnticholesteremic AgentsBlood Component RemovalCardiovascular DiseasesCause of DeathCholesterol, LDLCombined Modality TherapyEvidence-Based MedicineFatty Acids, Omega-3Fibric AcidsGermanyHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypercholesterolemiaHyperlipoproteinemiasHypertriglyceridemiaAnion Exchange ResinsAnticholesteremic AgentsCholesterol, LDLFatty Acids, Omega-3Fibric AcidsHydroxymethylglutaryl-CoA Reductase InhibitorsHypolipidemic AgentsNiacin

Identifiers

PMID21331642
OpenAlexW2028238607

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.