ArticlePlant cell reports2011
cAMP activates hyperpolarization-activated Ca2+ channels in the pollen of Pyrus pyrifolia.
Article in Plant cell reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 30 citations in OpenAlex.
- Non-Target Metabolomics Reveals Changes in Metabolite Profiles in Distant Hybrid Incompatibility BetweenPlants (Basel, Switzerland) · 2025Article
- Cross Talk Between Cyclic Nucleotides and Calcium Signaling Pathways in Plants-Achievements and Prospects.Frontiers in plant science · 2021Review
- Cyclic AMP: A Polyhedral Signalling Molecule in Plants.International journal of molecular sciences · 2020Review
- MgInternational journal of molecular sciences · 2020Article
- A Cyclic Nucleotide-Gated Channel, HvCNGC2-3, Is Activated by the Co-Presence of Na⁺ and K⁺ and Permeable to Na⁺ and K⁺ Non-Selectively.Plants (Basel, Switzerland) · 2018Article
- Calcium dynamics in tomato pollen tubes using the Yellow Cameleon 3.6 sensor.Plant reproduction · 2018Article
- Interplay between Ions, the Cytoskeleton, and Cell Wall Properties during Tip Growth.Plant physiology · 2018Review
- Cyclic Nucleotide Monophosphates and Their Cyclases in Plant Signaling.Frontiers in plant science · 2017Review
- Cyclic nucleotide-gated channel 18 is an essential Ca2+ channel in pollen tube tips for pollen tube guidance to ovules in Arabidopsis.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Apoplastic calmodulin promotes self-incompatibility pollen tube growth by enhancing calcium influx and reactive oxygen species concentration in Pyrus pyrifolia.Plant cell reports · 2014Article
- A cyclic nucleotide-gated channel (CNGC16) in pollen is critical for stress tolerance in pollen reproductive development.Plant physiology · 2013Article
- Cyclic nucleotide gated channels 7 and 8 are essential for male reproductive fertility.PloS one · 2013Article
- Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many signal-transduction processes in plant cells have been suggested to be triggered by signal-induced opening of calcium ion (Ca(2+)) channels in the plasma membrane. Cyclic nucleotides have been proposed to lead to an increase in cytosolic free Ca(2+) in pollen. However, direct recordings of cyclic-nucleotide-induced Ca(2+) currents in pollen have not yet been obtained. Here, we report that cyclic AMP (cAMP) activated a hyperpolarization-activated Ca(2+) channel in the Pyrus pyrifolia pollen tube using the patch-clamp technique, which resulted in a significant increase in pollen tube protoplast cytosolic-Ca(2+) concentration. Outside-out single channel configuration identified that cAMP directly increased the Ca(2+) channel open-probability without affecting channel conductance. cAMP-induced currents were composed of both Ca(2+) and K(+). However, cGMP failed to mimic the cAMP effect. Higher cytosolic free-Ca(2+) concentration significantly decreased the cAMP-induced currents. These results provide direct evidence for cAMP activation of hyperpolarization-activated Ca(2+) channels in the plasma membrane of pollen tubes, which, in turn, modulate cellular responses in regulation of pollen tube growth.
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