ArticleEuropean archives of psychiatry and clinical neuroscience2011
An epidemiologic and clinical overview of medical and psychopathological comorbidities in major psychoses.
Article in European archives of psychiatry and clinical neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Evaluating psychosis-specific effects of trauma exposure in early-onset and adult-onset psychosis.Psychological medicine · 2026Article
- Managing schizophrenia with affective, sexual, metabolic and substance-use comorbidities: pharmacological considerations from an expert consensus.Annals of general psychiatry · 2025Article
- The patient journey project in Italian mental health services: results from a co-designed survey on clinical interventions and current barriers to improve the care of people living with schizophrenia.Frontiers in psychiatry · 2024Article
- Clinical uses of Bupropion in patients with Parkinson's disease and comorbid depressive or neuropsychiatric symptoms: a scoping review.BMC neurology · 2022Article
- Economic Impact of Schizophrenia from a Hospital and Social Security System Perspective in Italy.Clinical drug investigation · 2021Article
- Peripheral blood lymphocyte subpopulations in patients with bipolar disorder type II.Scientific reports · 2019Article
- The Role of CXCR3 in Neurological Diseases.Current neuropharmacology · 2019Review
- Lack of Diagnostic Pluripotentiality in Patients at Clinical High Risk for Psychosis: Specificity of Comorbidity Persistence and Search for Pluripotential Subgroups.Schizophrenia bulletin · 2018Article
- Article
- Somatic Care with a Psychotic Disorder. Lower Somatic Health Care Utilization of Patients with a Psychotic Disorder Compared to Other Patient Groups and to Controls Without a Psychiatric Diagnosis.Administration and policy in mental health · 2016Article
- Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders.Microarrays (Basel, Switzerland) · 2016Article
- Lurasidone for the treatment of bipolar depression: an evidence-based review.Neuropsychiatric disease and treatment · 2015Review
- Monocyte and lymphocyte activation in bipolar disorder: a new piece in the puzzle of immune dysfunction in mood disorders.The international journal of neuropsychopharmacology · 2014Article
- The impact of repeated manic episodes and executive dysfunction on work adjustment in bipolar disorder.European archives of psychiatry and clinical neuroscience · 2014Article
- Chemokines in bipolar disorder: trait or state?European archives of psychiatry and clinical neuroscience · 2013Article
- The lifetime and past-year prevalence of dual diagnosis in people with schizophrenia across Europe: findings from the European Schizophrenia Cohort (EuroSC).European archives of psychiatry and clinical neuroscience · 2012Article
- Neuroglialpharmacology: myelination as a shared mechanism of action of psychotropic treatments.Neuropharmacology · 2012Review
- Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2011Article
- From generation of biomarkers to treatment and psychosocial aspects of psychosis.European archives of psychiatry and clinical neuroscience · 2011Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of comorbidity in major psychoses (e.g., schizophrenia and psychotic subtypes of bipolar disorder and major depressive disorder) seems to be the rule rather than the exception in both DSM-IV and ICD-10. Examining comorbidity in major psychoses, however, requires an investigation into the different levels of comorbidity (either full-blown and subsyndromal) which should be analyzed in both psychopathological and medical fields. On one hand, the high prevalence of psychiatric comorbidity in major psychoses may be the result of the current nosographic systems. On the other hand, it may stem from a common neurobiological substrate. In fact, comorbid psychopathological conditions may share a biological vulnerability, given that dysfunction in specific brain areas may be responsible for different symptoms and syndromes. The high rates of comorbidity in major psychoses require targeted pharmacological treatments in order to effectively act on both the primary diagnosis and comorbid conditions. Nevertheless, few controlled trials in comorbid major psychoses had been carried out and treatment recommendations in this field have mostly an empirical basis. The aim of the present article is to provide a comprehensive and updated overview in relation to epidemiological and clinical issues of comorbidity in major psychoses.
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Registered trials
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