Evidence map›Paper›PMID 21331452›Full record

ReviewStem cell reviews and reports2011

Stem cells in tooth tissue regeneration--challenges and limitations.

Bülend Inanç, Y Murat Elçin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Advances in Regenerative Medicine and Biomaterials.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  2. Article
  3. Article
  4. Imperative role of dental pulp stem cells in regenerative therapies: a systematic review.Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society · 2014
    Review
  5. Article
  6. Therapeutic potential of dental stem cells.Journal of tissue engineering
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bülend InançTissue Engineering, Biomaterials & Nanobiotechnology Laboratory, Ankara University Stem Cell Institute and Faculty of Science, Ankara, 06100, Turkey.
Y Murat Elçin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accelerated pace of research in the stem cell field in recent decades and the accumulated body of knowledge has spurred the interest in potential clinical applications of stem cells in all branches of medicine including regenerative dentistry. In humans, embryonic and adult stem cells are two major groups of cells that can serve as a donor source in tissue engineering strategies based on ex-vivo cellular expansion. It has been shown that adult stem cell populations are present in all examined living tissues of the organism, thus being a crucial source of tissue homeostasis and regeneration, and offering a target population for in situ stimulation of extensive tissue regeneration. Experimental findings indicate that in the complex structure of the tooth organ, both periodontal and endodontic tissues harbour adult stem cells with characteristics peculiar to early stages of cellular differentiation. Myriad of strategies incorporating both embryonic and adult stem cells for the regeneration of a particular tooth structure or the whole teeth were proposed; however their successful application to solve real problems encountered in the clinical practice of dentistry remains an elusive and challenging objective.

Indexed as

Cell DifferentiationCell ProliferationHumansRegenerationStem CellsStem Cell TransplantationTissue EngineeringTooth

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.