Evidence map›Paper›PMID 21331232›Full record

ArticleCommunicative & integrative biology2010

Biogenesis of extracellular vesicles in yeast: Many questions with few answers.

Débora L Oliveira, Ernesto S Nakayasu, Luna S Joffe, Allan J Guimarães, Tiago Jp Sobreira, Joshua D Nosanchuk, Radames Jb Cordero, Susana Frases, Arturo Casadevall, Igor C Almeida and 2 more

Abstract read
In one paragraph

Article in Communicative & integrative biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Selective DNA encapsulation in extracellular vesicles ofExtracellular vesicles and circulating nucleic acids · 2026
    Article
  3. Article
  4. Review
  5. Exosome: From biology to drug delivery.Drug delivery and translational research · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. The capsule ofVirulence · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. Mycobacterium avium Complex Extracellular Vesicles Attenuate Inflammation via Inducing IL-10.International journal of molecular and cellular medicine · 2018
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Débora L OliveiraLaboratório de Estudos Integrados em Bioquímica Microbiana; Instituto de Microbiologia Professor Paulo de Góes; Rio de Janeiro; Brazil.
Ernesto S Nakayasu
Luna S Joffe
Allan J Guimarães
Tiago Jp Sobreira
Joshua D Nosanchuk
Radames Jb Cordero
Susana Frases
Arturo Casadevall
Igor C Almeida
Leonardo Nimrichter
Marcio L Rodrigues

Funding

TOXICOLOGY PROJECTG12RR008124 · NCRR · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 1992 to 2011
$20.8M
TRAINING PROGRAM IN CELLULAR &MOLEC. BIOLOGY &GENETICST32GM007491 · NIGMS · YESHIVA UNIVERSITY · PI QUERY, CHARLES C · 1985 to 2021
$17.0M
Synergy of Host Defense Mechanisms in the LungR01HL059842 · NHLBI · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1997 to 2023
$7.4M
Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
PROTECTIVE ANTIBODIES FOR CRYPTOCOCCAL INFECTIONSR01AI033774 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1994 to 2014
$5.6M
Molecular Characterization of C. neoformans AntibodiesR37AI033142 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CASADEVALL, ARTURO · 2007 to 2016
$3.9M
Antibody Protection in HistoplamosisR01AI056070 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI NOSANCHUK, JOSHUA D · 2005 to 2009
$1.8M
Interhemispheric Research/Training in Infectious DiseaseD43TW007129 · FIC · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI TANOWITZ, HERBERT BERNARD · 2004 to 2013
$1.7M
MOLECULAR CHARACTERIZATION OF C NEOFORMANS ANTIBODIESR01AI033142 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1994 to 2006
$1.7M
FIC NIH HHS D43 TW007129NCRR NIH HHS G12 RR008124NHLBI NIH HHS R01 HL059842NIAID NIH HHS R01 AI033142NIAID NIH HHS R01 AI033774NIAID NIH HHS R01 AI052733NIAID NIH HHS R01 AI056070NIAID NIH HHS R37 AI033142NIGMS NIH HHS T32 GM007491
6 · The paper itself

Abstract

The cellular events required for unconventional protein secretion in eukaryotic pathogens are beginning to be revealed. In fungi, extracellular release of proteins involves passage through the cell wall by mechanisms that are poorly understood. In recent years, several studies demonstrated that yeast cells produce vesicles that traverse the cell wall to release a wide range of cellular components into the extracellular space. These studies suggested that extracellular vesicle release involves components of both conventional and unconventional secretory pathways, although the precise mechanisms required for this process are still unknown. We discuss here cellular events that are candidates for regulating this interesting but elusive event in the biology of yeast cells.

Indexed as

exosomeextracellular vesiclessecretiontrans-cell wall transportyeast box

Identifiers

PMID21331232
PMCPMC3038056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.