Evidence map›Paper›PMID 21331070›Full record

ArticleLeukemia2011

Relative fitness of hematopoietic progenitors influences leukemia progression.

C C Porter, D Baturin, R Choudhary, J DeGregori

Abstract readLetter
In one paragraph

Article in Leukemia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Immunosenescence and lymphomagenesis.Immunity & ageing : I & A · 2018
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. DNA damage checkpoints in stem cells, ageing and cancer.Nature reviews. Molecular cell biology · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C C Porter
D Baturin
R Choudhary
J DeGregori

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
POSTGRADUATE TRAINING IN PEDIATRIC ONCOLOGYT32CA082086 · NCI · UNIVERSITY OF COLORADO DENVER · PI GORE, LIA · 2000 to 2015
$4.1M
Colorado Program in Aging and CancerP20CA103680 · NCI · UNIVERSITY OF COLORADO DENVER · PI BYERS, TIM E · 2003 to 2007
$3.2M
Poor competition in hematopoietic stem/progenitor pools favors tumorigenesisR01CA109657 · NCI · UNIVERSITY OF COLORADO DENVER · PI DEGREGORI, JAMES V · 2005 to 2009
$1.1M
NCI NIH HHS P20 CA103680NCI NIH HHS P30 CA046934NCI NIH HHS R01 CA109657NCI NIH HHS T32 CA082086
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntimetabolites, AntineoplasticBone MarrowCells, CulturedDisease Models, AnimalDisease ProgressionFlow CytometryGene Knock-In TechniquesHematopoietic Stem CellsHumansLeukemia, ExperimentalMiceMyeloproliferative DisordersOncogene Proteins, FusionThioguanineAntimetabolites, AntineoplasticMLL-AF9 fusion protein, mouseOncogene Proteins, FusionThioguanine

Identifiers

PMID21331070
PMCPMC3670417

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.