ReviewMolecules (Basel, Switzerland)2011
Design and screening of M13 phage display cDNA libraries.
Review in Molecules (Basel, Switzerland), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Recent progress of gas sensors toward olfactory display development.Nano convergence · 2025Review
- Development and application of an interbacterial DNA delivery system based on M13 bacteriophage.Archives of microbiology · 2025Article
- Review
- Advancement in the development of single chain antibodies using phage display technology.PeerJ · 2024Article
- Engineered M13 phage as a novel therapeutic bionanomaterial for clinical applications: From tissue regeneration to cancer therapy.Materials today. Bio · 2023Review
- Extracellular Vesicle Molecular Profiling for Diagnostic Purposes: An Application of Phage Display Technology.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Phage ImmunoPrecipitation Sequencing (PhIP-Seq): The Promise of High Throughput Serology.Pathogens (Basel, Switzerland) · 2022Review
- High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing.Journal of virology · 2020Article
- Review
- Exhaustive Search of the Receptor Ligands by the CyCLOPS (Cytometry Cell-Labeling Operable Phage Screening) Technique.International journal of molecular sciences · 2020Article
- Mapping Protein-Protein Interaction Interface Peptides with Jun-Fos Assisted Phage Display and Deep Sequencing.ACS synthetic biology · 2020Article
- In Vivo Translation of Peptide-Targeted Drug Delivery Systems Discovered by Phage Display.Bioconjugate chemistry · 2018Review
- Identification and Characterization of Novel Fc-Binding Heptapeptides from Experiments and Simulations.Polymers · 2018Article
- 1st German Phage Symposium-Conference Report.Viruses · 2018Article
- cDNA phage display for the discovery of theranostic autoantibodies in rheumatoid arthritis.Immunologic research · 2017Review
- Application of M13 phage display for identifying immunogenic proteins from tick (Ixodes scapularis) saliva.BMC biotechnology · 2015Article
- In Vitro Selection of Cancer Cell-Specific Molecular Recognition Elements from Amino Acid Libraries.Journal of immunology research · 2015Review
- Bacteriophages and medical oncology: targeted gene therapy of cancer.Medical oncology (Northwood, London, England) · 2014Review
- A protocol for phage display and affinity selection using recombinant protein baits.Journal of visualized experiments : JoVE · 2014Article
- Interaction analysis through proteomic phage display.BioMed research international · 2014Review
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The last decade has seen a steady increase in screening of cDNA expression product libraries displayed on the surface of filamentous bacteriophage. At the same time, the range of applications extended from the identification of novel allergens over disease markers to protein-protein interaction studies. However, the generation and selection of cDNA phage display libraries is subjected to intrinsic biological limitations due to their complex nature and heterogeneity, as well as technical difficulties regarding protein presentation on the phage surface. Here, we review the latest developments in this field, discuss a number of strategies and improvements anticipated to overcome these challenges making cDNA and open reading frame (ORF) libraries more readily accessible for phage display. Furthermore, future trends combining phage display with next generation sequencing (NGS) will be presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.